Direct effect of chlorine dioxide, zinc chloride and chlorhexidine solution on the gaseous volatile sulfur compounds

Kim, Ju‐Sik; Park, Ji-Woon; Kim, Dae Jung; Kim, Young-Ku; Lee, Jeong-Yun

doi:10.3109/00016357.2014.887770

Cited by 9 publications

(10 citation statements)

References 33 publications

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“…Zn 2+ , chlorine dioxide (ClO 2 ), and green tea catechins have deodorant activities in addition to their antibacterial activities (Kim, Park, Kim, Kim, & Lee, ; Suzuki et al, ; Yasuda & Arakawa, ). Among metal ions, Zn 2+ , along with ions of silver, copper and cadmium, bind directly to VSC, suppressing volatilization (Suzuki et al, ).…”

Section: Inhibition Of Oral Malodormentioning

confidence: 99%

“…As described above, Zn 2+ is generally combined with other antibacterial agents in products for controlling oral malodor, and a mouthwash containing Zn 2+ had immediate inhibitory activity against oral malodor (Roldán et al, ; Young et al, ). ClO 2 and the chlorite anion (ClO 2 − ) oxidize VSCs directly into non‐malodorous products, thus consuming the amino acids that act as precursors to VSCs (Kim et al, ). A randomized double‐blind crossover placebo‐controlled clinical trial showed that mouth rinsing with ClO 2 effectively reduced morning malodor for 4 hr in healthy volunteers (Shinada et al, ).…”

Section: Inhibition Of Oral Malodormentioning

confidence: 99%

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Induction and inhibition of oral malodor

Suzuki

Yoneda

Takeshita

et al. 2019

Molecular Oral Microbiology

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Volatile sulfur compounds (VSCs) such as hydrogen sulfide (H2S) and methyl mercaptan (CH3SH) are the main components of oral malodor, and are produced as the end products of the proteolytic processes of oral microorganisms. The main pathway of proteolysis is the metabolism of sulfur‐containing amino acids by gram‐negative anaerobic bacteria. Gram‐positive bacteria may promote VSC production by gram‐negative anaerobes by cleaving sugar chains from glycoproteins and thus providing proteins. A large variety of bacteria within the oral microbiota are thought to be involved in the complex phenomenon of halitosis. Oral microbiota associated with a lack of oral malodor, oral microbiota associated with severe and H2S‐dominant oral malodor, and oral microbiota associated with severe and CH3SH‐dominant oral malodor have been distinguished through molecular approaches using the 16S rRNA gene. Pathological halitosis may primarily be addressed through treatment of causative diseases. In all cases, plaque control is the basis of oral malodor control, and dentifrices, mouthwashes, and functional foods play a supplementary role in addition to brushing. Recently, the use of natural ingredients in products tends to be favored due to the increase in antibiotic‐resistant strains and the side effects of some chemical ingredients. In addition, probiotics and vaccines are expected to offer new strategies for improving the oral conditions through mechanisms other than antibacterial agents.

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Section: Inhibition Of Oral Malodormentioning

confidence: 99%

Section: Inhibition Of Oral Malodormentioning

confidence: 99%

Induction and inhibition of oral malodor

Suzuki

Yoneda

Takeshita

et al. 2019

Molecular Oral Microbiology

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“…Several chlorine‐containing over‐the‐counter mouthrinses are currently commercially available . Most of these preparations are sold as anti‐halitosis products , but they are also known to have antimicrobial activities .…”

Section: Antimicrobial Mouthrinsesmentioning

confidence: 99%

Improving periodontal outcomes: merging clinical and behavioral science

Wilder¹,

Bray

2016

Periodontology 2000

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New data indicate that periodontal diseases are much more prevalent than previously thought, which means that there are large numbers of patients who will need to be diagnosed and treated for periodontal disease in a general dental practice. Oral hygiene procedures performed by patients between office visits are important for gingival health. No particular type of toothbrush has consistently been shown to have superior plaque-removal ability over another. Although studies on powered brushes have shown evidence for efficacy of biofilm removal and increased patient compliance, they are of short duration, making evaluation of long-term effects difficult to achieve. Interdental cleaning with dental floss can be effective but it is technique-sensitive. Interdental brushes have been shown to be superior to floss in plaque index scores, but not in gingival inflammation reduction. A systematic review of oral irrigation reported a beneficial adjunctive effect on bleeding and gingival indices and pocket depth. Antimicrobials in mouthrinses and toothpastes have shown significant reductions in plaque and gingivitis when used correctly. Even though it is considered essential for patients to utilize biofilm-removal techniques on a frequent basis, studies on adherence show that approximately 30-60% of health information is forgotten within 1 h, and 50% of health recommendations are not followed. Incorporating psychosocial aspects of behavioral change, including well-established counseling strategies, such as motivational interviewing, may elicit improved patient outcomes.

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“…It has been reported that a combination of Zn 2+ and CHX or CPC inhibited VSC formation synergistically [29]. ClO 2 and chlorite anion (ClO 2 -) also oxidize VSCs directly into non-malodorous products, which consumes the amino acids that act as precursors to VSCs [30,31]. A randomized double-blind crossover placebo-controlled clinical trial found that mouth rinsing with ClO 2 effectively reduced morning malodor for 4 h in healthy volunteers [32].…”

Section: Chemical Agentsmentioning

confidence: 99%