Direct intraperitoneal insemination and controlled ovarian hyperstimulation in subfertile couples

Rhouma, Khémaïs Ben; Miled, Elyas Ben; Marzouk, Ahmed; Rihani, M.; Bakır, Mehmet

doi:10.1007/bf02211807

Cited by 3 publications

(2 citation statements)

References 20 publications

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“…DIPI can be chosen as a first line treatment in patients with unsolved or recurrent isthmic stenosis where tubal patency has been confirmed, no intrauteriune contour defects exist, and there is no profound male factor infertility [8-10]. Previous randomized study comparing pregnancy rates after IPI and standard IUI showed roughly equivalent outcomes [10].…”

Section: Discussionmentioning

confidence: 99%

Successful pregnancy by direct intraperitoneal insemination in an infertile patient with failure of recanalization of isthmic stenosis after laparoscopic radical trachelectomy

et al. 2014

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Radical trachelectomy is a promising fertility-sparing treatment for patients with early stage cervical cancer who want to preserve their fertility. However, isthmic stenosis occurs frequently in patients who received radical trachelectomy and it is one of the causes of infertility following radical trachelectomy. Moreover, despite the treatment for recanalization of isthmic stenosis, recanalization can fail or isthmic stenosis can recur. Herein we report a successful pregnancy and birth by direct intraperitoneal insemination in an infertile woman with failure of recanalization of isthmic stenosis after laparoscopic radical trachelectomy.

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Section: Discussionmentioning

confidence: 99%

Successful pregnancy by direct intraperitoneal insemination in an infertile patient with failure of recanalization of isthmic stenosis after laparoscopic radical trachelectomy

et al. 2014

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“…Intraperitoneal insemination (IPI) warrants consideration in such cases of cervical stenosis where tubal patency has been confirmed, no intrauteriune contour defects exist, and there is no profound male factor infertility diagnosis [11-13]. As with the more commonly performed IUI, the efficacy of IPI is directly related to the overall spermatozoa concentration, motility, and morphology [14,15].…”

Section: Discussionmentioning

confidence: 99%

Intrauterine pregnancy following low-dose gonadotropin ovulation induction and direct intraperitoneal insemination for severe cervical stenosis

Sills

Palermo

2002

BMC Pregnancy Childbirth

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BackgroundWe present a case of primary infertility related to extreme cervical stenosis, a subset of cervical factor infertility which accounts for approximately 5% of all clinical infertility referrals.Case presentationA 37 year-old nulligravida was successfully treated with ovulation induction via recombinant follicle stimulating hormone (FSH) and direct intraperitoneal insemination (IPI). Anticipating controlled ovarian hyperstimulation with in vitro fertilization/embryo transfer (IVF), the patient underwent hysteroscopy and cervical recanalization, but safe intrauterine access was not possible due to severe proximal cervical stricture. Hysterosalpingogram established bilateral tubal patency and confirmed an irregular cervical contour. Since the cervical canal could not be traversed, neither standard intrauterine insemination nor transcervical embryo transfer could be offered. Prepared spermatozoa were therefore placed intraperitoneally at both tubal fimbria under real-time transvaginal sonographic guidance using a 17 gage single-lumen IVF needle. Supplementary progesterone was administered as 200 mg/d lozenge (troche) plus 200 mg/d rectal suppository, maintained from the day following IPI to the 8th gestational week. A singleton intrauterine pregnancy was achieved after the second ovulation induction attempt.ConclusionsIn this report, we outline the relevance of cervical factor infertility to reproductive medicine practice. Additionally, our andrology evaluation, ovulation induction approach, spermatozoa preparation, and insemination technique in such cases are described.

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Intraperitoneal Insemination in Mammals: A Review

Yániz

López-Béjar

Santolaria

et al. 2002

Reprod Domestic Animals

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This review focuses on factors associated with the development of intraperitoneal insemination in mammals. Findings to date indicate that fertility improves as the sperm cell concentration rises, but that the optimal sperm number differs in each species. Sperm washing before intraperitoneal insemination favours fertility. Peritoneal fluid shows a variable effect on spermatozoa, depending on the hormonal status of the female. The optimal time for insemination appears to be just prior to ovulation. The technique may be performed either through the abdominal or the vaginal wall. Verification of sperm deposition in the proximity of the ovaries improves fertility rates. Although associated with some risk of infection and an immune reaction against spermatozoa, the intraperitoneal technique rarely gives rise to severe anaphylactic shock, peritonitis, adhesion formation and the production of anti-sperm antibodies and these complications may be prevented by adequate sperm pretreatment and antibiotic therapy. The success of intraperitoneal insemination in humans, with results comparable with those of intrauterine insemination in the treatment of infertility, suggest the potential use of this technique in domestic mammals, especially in those in which intrauterine insemination poses practical difficulties. Some of the methods applied in human intraperitoneal insemination, such as confirming the position of the needle in the peritoneal cavity, and sperm pre-treatments might also improve results in domestic species. Conversely, the use of the animal model should help to develop some aspects of this technique in humans.

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Direct intraperitoneal insemination and controlled ovarian hyperstimulation in subfertile couples

Abstract: The pregnancy rate was 33.3% for all couples and 15.0% for all cycles.

Cited by 3 publications

References 20 publications

Successful pregnancy by direct intraperitoneal insemination in an infertile patient with failure of recanalization of isthmic stenosis after laparoscopic radical trachelectomy

Successful pregnancy by direct intraperitoneal insemination in an infertile patient with failure of recanalization of isthmic stenosis after laparoscopic radical trachelectomy

Intrauterine pregnancy following low-dose gonadotropin ovulation induction and direct intraperitoneal insemination for severe cervical stenosis

Intraperitoneal Insemination in Mammals: A Review

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