In-situ high energy X-Ray diffraction (HEXRD) was used on compositionally graded steels to study the effect of substitutional elements on ferrite growth kinetics in Fe-C-X and Fe-C-X-Y systems. Two systems were selected to illustrate the applicability of the combinatorial approach in studying such transformations, Fe-C-Mn and Fe-C-Mn-Mo. Comparison between the measured ferrite growth kinetics using HEXRD and the predicted ones using Para-Equilibrium (PE) and Local Equilibrium with Negligible Partitioning (LENP) models indicates that the fractions reached at the stasis of transformation are lower than the predicted ones. Experiments indicated a deviation of measured kinetics from both PE and LENP models when increasing Mn and decreasing Mo (in Fe-C-Mn-Mo system). The large amount of data that can be obtained using this approach can be used for validating existing models describing ferrite growth kinetics.Quantum Beam Sci. 2019, 4, 1 2 of 17 is more complex than these limit cases. To explain this observation, it has been proposed that the interactions of solutes with the moving interface, while ignored in the two aforementioned models, lead to substantial dissipation of energy when the transformation occurs with negligible partitioning [14,15]. These interactions are known to exist because they lead to a compositional heterogeneity, or segregation, at the transformation interface that was experimentally measured using atom probe tomography (APT) or analytical transmission electron microscopy (TEM) [16][17][18]. The transport of this compositional heterogeneity during the transformation is the source of the additional dissipation termed solute drag (SD). Two different, but equivalent, formalisms were developed to express the amount of energy dissipated by solute drag [15,19]. This effect was integrated into a variety of models that displayed a better aptitude at predicting kinetics for broad ranges of composition and temperature in ternary systems [13,20,21]. One of the most notable characteristics of those models is their capability of describing the transition from PE to LENP transformation rates encountered in certain conditions. Attempts at generalizing those models to quaternary systems, containing two substitutional species, showed mixed results, which highlights the new questions they raise [22,23]. While they allow the description of complex interface behaviors, they require quantitative knowledge of thermodynamics in the interface, as a function of temperature and alloy composition [3].The effect of alloy composition can be tackled using a combinatorial approach on compositionally-graded alloys [24]. Such materials, usually made by joining dissimilar alloys subsequently heat-treated to promote interdiffusion, enable the exploration of a multitude of compositions, leading to maps of the composition-dependence of microstructures in a single step. This methodology is being actively developed in materials science [25], both from the viewpoint of microstructures [26] and from the viewpoint of related properties ...