Direction Selectivity in the Retina and Beyond

Reinhard, Katja; Kühn, Norma Krystyna; Farrow, Karl

doi:10.1016/b978-0-12-809324-5.24217-x

Cited by 1 publication

(2 citation statements)

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“…The respective ganglion cells fall into two categories: ON DS RGCs, which respond to light increments, and ON-OFF DS RGCs, which respond to light increments and decrements (Figure 3a,b). The presynaptic circuits of ON and ON-OFF DS RGCs overlap and compute motion direction by shared mechanisms, while unique mechanisms differentiate the speed and contrast preferences of ON and ON-OFF DS RGCs to match their behavioral functions (Mauss et al 2017, Reinhard et al 2020, Wei 2018.…”

Section: Direction Selectivitymentioning

confidence: 99%

“…ON-OFF DS RGC axons preferentially target the dLGN of the thalamus and the SC, whereas ON DS RGC axons preferentially target nuclei of the accessory optic system (AOS). Recent studies have begun to uncover how downstream pathways process DS RGC inputs to guide behavior , Reinhard et al 2020.…”

Section: Downstream Pathways and Behavioral Significance Of Retinal D...mentioning

confidence: 99%

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Feature Detection by Retinal Ganglion Cells

Kerschensteiner

2022

Annu. Rev. Vis. Sci.

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Retinal circuits transform the pixel representation of photoreceptors into the feature representations of ganglion cells, whose axons transmit these representations to the brain. Functional, morphological, and transcriptomic surveys have identified more than 40 retinal ganglion cell (RGC) types in mice. RGCs extract features of varying complexity; some simply signal local differences in brightness (i.e., luminance contrast), whereas others detect specific motion trajectories. To understand the retina, we need to know how retinal circuits give rise to the diverse RGC feature representations. A catalog of the RGC feature set, in turn, is fundamental to understanding visual processing in the brain. Anterograde tracing indicates that RGCs innervate more than 50 areas in the mouse brain. Current maps connecting RGC types to brain areas are rudimentary, as is our understanding of how retinal signals are transformed downstream to guide behavior. In this article, I review the feature selectivities of mouse RGCs, how they arise, and how they are utilized downstream. Not only is knowledge of the behavioral purpose of RGC signals critical for understanding the retinal contributions to vision; it can also guide us to the most relevant areas of visual feature space. Expected final online publication date for the Annual Review of Vision Science, Volume 8 is September 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

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Section: Direction Selectivitymentioning

confidence: 99%

Section: Downstream Pathways and Behavioral Significance Of Retinal D...mentioning

confidence: 99%