Discrimination Between Benign and Malignant Lesions in the Breast with Restriction Spectrum Imaging on a Screening Breast MRI Cohort

Abstract

Diffusion weighted imaging (DWI) holds great potential in improving specificity of findings detected on contrast enhanced breast MRI. Restriction spectrum imaging (RSI), an advanced diffusion imaging model, has potential in discriminating between malignant and fibroglandular breast tissue. In this abstract, we evaluate RSI’s performance in differentiating malignant from benign lesions in a prospective study performed on a breast screening population. All lesions were biopsy proven. The breast RSI model allowed discrimination between malignant, high-risk and low-risk benign lesions and healthy fibroglandular tissue.