Disease in a dairy herd associated with the introduction and spread of bovine virus diarrhoea virus

Abstract

In January 1982 an outbreak of diarrhoea among adult dairy cows in a closed herd of approximately 200 milking animals was shown to be caused by the introduction of bovine virus diarrhoea virus (BVDV). Affected animals showed a significant reduction in milk yield. One animal died and four were culled. Eight cows aborted and one weak calf was born. Of 121 calves born that year, 26 died, mostly from pneumonia, but five aged from three weeks to five months had enteric lesions of mucosal disease. Subsequent investigations of the whole herd in 1983 and 1984 showed that virus spread among the adults was slow and that BVDV continued to make a major contribution to calf losses. Again the greatest cause of loss was suppurative or fibrinous pneumonia. Overall, BVDV was isolated from 36 animals. Isolation of virus from a wide range of tissues of individual animals confirmed that they were viraemic at death. Viruses from calves dying of pneumonia and from aborted fetuses were non-cytopathic in tissue culture. Isolates showing varying degrees of cytopathogenicity were obtained only from tissues of one calf with a congenital neurological defect and the seven animals with enteric lesions consistent with a diagnosis of mucosal disease. Blood from all 89 BVDV antibody-free animals older than three months was tested for the presence of BVDV. Altogether, 12 calves were identified as persistently viraemic and all were apparently healthy when bled. Only two matured normally, four grew poorly and six died.(ABSTRACT TRUNCATED AT 250 WORDS)

Besi sığırlarında solunum sistemi virüslerinin seroprevalansı ve persiste BVD virüs enfeksiyonu tespiti

“…Gebe olmayan hayvanlarda ateş, nazal ve oküler akıntı, eroziv stomatitis, löykopeni, ishal ve ineklerde süt veriminde azalma gözlemlenir (24). Gebe hayvanlardaki enfeksiyon tablosu ise biyotipine ve gebeliğin dönemine bağlı olarak persiste enfekte yavru doğumları, anomalili yavru doğumları ve abort oluşumu ile sonuçlanabilmekte-dir (4).…”

Prevalence of bovine viral diarrhea virus infection in bulls in artificial insemination centers in Poland

“…Bovine viral diarrhea virus (BVDV) is a common cattle pathogen with world-wide distribution (Baker, 1987;Houe, 1995). This widespread occurrence makes BVDV infection economically significant (Duffel et al, 1986;Houe, 1995).…”

“…Also, reduced conception rates in seronegative cows when using BVDVcontaminated semen can be observed (McClurkin et al, 1979;Whitmore et al, 1981). Moreover, animals acutely or persistently infected with BVDV may look healthy, and clinical examination will not provide any suspicion of BVDV infection (Coria and McClurkin, 1978;Cutlip et al, 1980;Barber et al, 1985). Therefore, bulls should be tested, and only virus-negative animals should be introduced into artificial insemination (AI) centers.…”

Distribution of Cytopathic and Noncytopathic Bovine Viral Diarrhea Virus Antigens in Tissues of Calves following Acute Experimental Infection

“…l4 However, disease with high mortality rates has also been reported. 4,13,18,30 Cytopathic (CP) and noncytopathic (NCP) BVDV have been recovered from field cases of disease, 3,18 and studies on experimental infections in cattle have demonstrated that both BVDV biotypes are capable of causing mild or severe acute enteritis. 8,9,11,17,20,34 Mixed populations of CP and NCP BVDV have been detected in reference strains.…”