Diseases and Surgery of the Lens

Stoppini, Riccardo; McMullen, Richard J.

doi:10.1002/9781119782285.ch7

Cited by 1 publication

(5 citation statements)

References 107 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another possible explanation is the occurrence of small tears in the posterior lens capsule through which small lens fragments could dislodge the vitreous intraoperatively, which were not detected during surgery. Although the migration of lens remnants in the vitreous body/chamber could be associated with potentially severe concomitant complications [19], such complications were not observed in this study. The small size of the migrated fragments may most likely explain this outcome.…”

Section: Discussionmentioning

confidence: 62%

“…Previously reported rates of postoperative RD are lower, ranging 6.4-25% [6,8]. The differences may be explained by varying surgical techniques and intraoperative complications, perioperative medical management, cataract aetiology (more preoperative pathological findings) and study design [7,19,32,33]. The evaluation of the postoperative course in the present study was performed by a veterinarian in all cases, whereas the postoperative outcome was partly based on telephone interviews with the owners in previous reports [6][7][8].…”

Section: Discussionmentioning

confidence: 83%

“…Based on history and preoperative findings associated with previous uveitis in all cases, an increased risk of postoperative persistent active uveitis was assumed in the horses included in the current study [6,7,19]. To avoid additional postoperative ocular irritation, an intraocular lens was not applied in any case [26].…”

Section: Discussionmentioning

confidence: 99%

“…Horses were subsequently intubated and positioned in left or right lateral recumbency, depending on the affected eye. The periocular region was prepared for surgery using standard methods [19]. During general anaesthesia, the end-tidal isoflurane concentration (FE'Iso) (Isofluran-CP 1 mg/mL, CP-Pharma Handelsgesellschaft, Burgdorf, Germany) was set at approximately 3.5-4.5% depending on the depth of anaesthesia.…”

Section: Pe-ppvmentioning

confidence: 99%

“…Uveitis-associated cataract is a particular challenge for the equine ophthalmologist. In this case, both the cataract and the uveitis must be treated, and the incidence of postsurgical persistent active uveitis is high [6,7,19]. The aim of this study was to assess the intraoperative course and postsurgical outcome of PE-PPV for the management of uveitisassociated cataracts in 32 eyes of 28 horses.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Phacoemulsification Combined with Pars Plana Vitrectomy: Outcome in Horses with Acquired Cataracts Associated with Uveitis

Kalinovskiy,

Leser,

Ehrle

et al. 2024

Animals

View full text Add to dashboard Cite

Background: Cataracts resulting from equine recurrent uveitis (ERU) or other forms of uveitis are usually associated with rapid progression. ERU is the most common ocular disease cause of blindness and cause of cataracts in horses. The necessity for the posterior capsulorhexis (PC) during phacoemulsification (PE) is controversial. This study aimed to evaluate vision and complications after PE combined with pars plana vitrectomy (PPV) in horses with uveitis-associated cataracts and compare the PE technique with and without posterior capsulorhexis. Methods: Thirty-two eyes of 28 horses with uveitis-associated cataracts aged 14 months to 19.6 years were treated with PE-PPV under identical conditions. Twenty-three eyes of 21 horses were affected by an ERU-associated (ERU group), and nine eyes of 7 horses were affected by cataracts related to uveitis with pathogenesis different to ERU (non-ERU group). PE-PPV was performed in 12 eyes of 10 horses (PC group) and 20 eyes of 18 horses without posterior capsulorhexis (NPC group). Follow-up examination was performed at a mean of 1.7 ± 1.8 years postoperatively (range: 1 month–6.4 years). Results: In the period up to 1 month postoperatively, 17/20 (85%) NPC-eyes and 8/12 (67%) PC-eyes (total: 25/32 [78%]) were visual. From 1–6 months postoperatively, 16/20 (80%) NPC-eyes and 7/12 (58.3%) PC-eyes (total: 23/32 [72%]), and from 6–12 months, 7/11 (63.6%) NPC-eyes and 3/8 (37.5%) PC-eyes (total: 10/19 [52.6%]) were visual. From 12–18 months postoperatively, 3/7 (42.9%) NPC-eyes and 2/9 (22.2%) PC-eyes (total: 5/16 [31.3%]), and from 18–24 months, 3/8 (37.5%) NPC-eyes and 1/8 (12.5%) PC-eyes (total: 4/16 [25%]) were visual. After 24 months postoperatively, 2/7 (28.6%) NPC-eyes and 1/8 (12.5%) PC-eyes (total: 3/15 [20%]) were visual. Despite the higher number of visual eyes in the NPC group at each time point, differences were not significant. No obvious differences regarding postsurgical vision were observed between the ERU- and non-ERU groups at each time point. In the overall population, a significant decrease in the number of eyes with postoperative active uveitis was observed during the follow-up examinations (p < 0.001). A significant increase in the number of eyes that were blind due to retinal detachment was observed in the overall patient population as the examination period progressed (p < 0.001). Retinal detachment was the sole long-term cause of blindness. Conclusions: In horses diagnosed with uveitis-associated cataracts and treated with PE-PPV, no persistent active uveitis was observed in the present study during follow-up examinations. However, the proportion of eyes that were blind due to retinal detachment increased. Whilst PE-PPV may prevent postsurgical persistent active uveitis and remove lens opacity, the prognosis for a visual outcome is guarded. A superior outcome in postsurgical vision was observed in the NPC group. However, caution is required when interpreting these results due to several factors that affect the independent comparison of the surgical groups.

show abstract

Section: Discussionmentioning

confidence: 62%