Disparity in pathologic and clinical lymph node staging in oral tongue carcinoma

Abstract

At present, storage capacities of single tank and tank farm have been greatly increasing. This change poses a real challenge for the applicability of current design standards. This article focuses on the applicability of safety spacing between tanks, which is one of the most important parameters of tank farm safety design. Taking PHAST and FDS as main research tools, the consequences of representative accidental scenarios were evaluated for different sizes of oil tanks to study the safety performance change caused by the increase of capability. The research results show that, when current standards are used to design the safety spacing between tanks, the safety performance increases as the capability increases. Considering the high property density, it is suggested that a higher safety performance objective has to be chosen when designing the safety spacing for ultra‐large oil tanks. © 2012 American Institute of Chemical Engineers Process Saf Prog, 2012.

Intra-arterial chemoradiotherapy for locally advanced oral cavity cancer: analysis of therapeutic results in134 cases

“…No randomised controlled trials have yet been performed to compare the effectiveness of surgery with chemoradiation, and the usefulness of chemoradiation therapy involving systemic chemotherapy thus remains to be clarified. After surgery, the 5-year survival rate ranged from 27 to 60% of stage III patients, while it ranged from approximately 12 to 40% of stage IV patients (Chen et al, 1999;Sessions et al, 2002;Greenberg et al, 2003;Lo et al, 2003;Gorsky et al, 2004;Liao et al, 2006;Fan et al, 2007); our results were therefore similar to the results after surgery. In particular, the results of arterial injection therapy by cisplatin with sodium thiosulphate were excellent.…”

Oral squamous cell carcinoma: Review of prognostic and predictive factors

“…2) have variable incidence and are widely accepted as one of the major prognostic factors in patients with OSCC. [32][33][34][35] Their presence is associated with a decrease in global survival to roughly half as well as with higher recurrence rates. 24,[34][35][36] Cervical node metastases may be classified into 2 distinct categories: overt (clinical) or nonovert (occult).…”

“…36 A retrospective study involving 266 patients who had previously undergone surgery and cervical node dissection, revealed that 34% of those initially classified as cN0 had, in fact, occult metastatic disease (pN1). 33 Therefore, staging based on pathologic analysis following neck dissection should be considered, in order to identify high-risk patients who may benefit from adjuvant therapy, because those with node metastases show significantly lower survival rates than those with disease-free nodes. 33,34 Tumor thickness.…”

“…33 Therefore, staging based on pathologic analysis following neck dissection should be considered, in order to identify high-risk patients who may benefit from adjuvant therapy, because those with node metastases show significantly lower survival rates than those with disease-free nodes. 33,34 Tumor thickness. The risk of nodal metastases and mortality rates vary directly with the thickness of the primary tumor.…”

“…3), ECS is a noticeably important prognostic factor, associated with higher locoregional recurrence rates, distant metastases, and lower survival rates. 33,35,36 Some authors report a decrease in survival rates between 29% and 60%, as well as an increase in nodal metastases rates, when ECS is observed 34 ; others show 5-year survival rates of 21% in patients with ECS vs 64% for those with intranodal metastases. 35 A descriptive evaluation system of ECS extension subdivides it into macro-and microscopic.…”