Abstract:BackgroundChanges in the brain’s default mode network (DMN) in the resting state are closely related to autism spectrum disorder (ASD). Module segmentation can effectively elucidate the neural mechanism of ASD and explore the intra- and internetwork connections by means of the participation coefficient (PC).MethodsResting-state fMRI data from 269 ASD patients and 340 healthy controls (HCs) were used in the current study. The PC of brain network modules was calculated and compared between ASD subjects and HCs. … Show more
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