Objective To identify weight gain trends of infants with Robin sequence (RS) treated by the Stanford Orthodontic Airway Plate treatment (SOAP). Design Retrospective longitudinal cohort study. Setting Single tertiary referral hospital. Patients Eleven infants with RS treated with SOAP. Interventions Nonsurgical SOAP. Main Outcome Measures Body weight, Weight-for-age (WFA) Z-scores, and WFA percentiles at birth (T0), SOAP delivery (T1), SOAP graduation (T2), and 12-months old (T3). Results Between T0 and T1, the weight increased but the WFA percentile decreased from 36.5% to 15.1%, and the Z-score worsened from −0.43 to −1.44. From T1 to T2, the percentile improved to 22.55% and the Z-score to −0.94. From T2 to T3, the percentile and the Z-scores further improved to 36.59% and −0.48, respectively. Conclusions SOAP provided infants experiencing severe respiratory distress and oral feeding difficulty with an opportunity to gain weight commensurate with the WHO healthy norms without surgical intervention.