Distinct skin microbiome modulation following different topical acne treatments in mild acne vulgaris patients: A randomized, investigator‐blinded exploratory study

Wongtada, Chanidapa; Prombutara, Pinidphon; Asawanonda, Pravit; Noppakun, Nopadon; Kumtornrut, Chanat; Chatsuwan, Tanittha

doi:10.1111/exd.14779

Cited by 7 publications

(3 citation statements)

References 36 publications

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“…Dermocosmetics have been increasingly used for acne either as monotherapy (in mild cases) or as adjunct to prescription therapy to improve efficacy and adverse effects of prescribed acne medications 70,71 . The active ingredients in dermocosmetics may support the skin barrier function, positively impact the skin microbiome, limit exposure to environmental factors such as ultraviolet radiation, and decrease inflammation via immunomodulation 70–72 . Among 566 acne patients, adherence to specific adjuvant treatments (facial cleansing, emollient, moisturizing, and lenitive specific topical products) was associated with a 2.4 increase in the probability of adherence to pharmacological treatment 73 .…”

Section: Resultsmentioning

confidence: 99%

“…70,71 The active ingredients in dermocosmetics may support the skin barrier function, positively impact the skin microbiome, limit exposure to environmental factors such as ultraviolet radiation, and decrease inflammation via immunomodulation. [70][71][72] Among 566 acne patients, adherence to specific adjuvant treatments (facial cleansing, emollient, moisturizing, and lenitive specific topical products) was associated with a 2.4 increase in the probability of adherence to pharmacological treatment. 73 In another study, concomitant use of heparinoid moisturizers with adapalene decreased side effects commonly associated with adapalene (dry skin, exfoliation, erythema and a burning sensation) and elongated the treatment period.…”

Section: Reducing Adverse Reactionsmentioning

confidence: 99%

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Adherence to treatment in dermatology: Literature review

Lo,

Lovell,

Greenzaid

et al. 2024

JEADV Clinical Practice

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Poor adherence to therapies in dermatology remains a prevalent issue associated with treatment failure, poor clinical outcomes, and reduced quality of life. The aim of this review is to summarize the current literature on medical adherence specifically in dermatology, including ways to measure treatment adherence, factors contributing to nonadherence, interventions to increase adherence, and the impact of adherence on patient outcomes. We conducted a MEDLINE search between the years 2006 and 2023 using the following term: [adherence AND dermatology AND treatment]. The search was limited to English article types: clinical study, clinical trial, observational study, and randomized controlled trials in human subjects. The literature search yielded 323 articles. 52 of these articles met the inclusion criteria and were reviewed to define, measure, understand, and suggest means to increase adherence in dermatology. Additional articles were added from in text citations. Adherence can be measured using subjective and objective methods. Patient‐, treatment‐, and disease‐centered factors are important to consider when prescribing medications and implementing interventions to increase adherence. Reducing treatment adverse reactions, simplifying treatment regimens, and eHealth, education, communication, and psychological interventions are associated with improved adherence and disease outcomes. Understanding and enhancing adherence is crucial because of its impact on costs, treatment efficacy, and healthcare outcomes.

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Section: Resultsmentioning

confidence: 99%

Section: Reducing Adverse Reactionsmentioning

confidence: 99%

Adherence to treatment in dermatology: Literature review

Lo,

Lovell,

Greenzaid

et al. 2024

JEADV Clinical Practice

View full text Add to dashboard Cite

show abstract

“…Preserving the integrity of the skin barrier stands as an important mechanism through which dermocosmetics can contribute to acne treatment. Epidermal barrier dysfunction can be inherent to the condition itself or result from acne treatment with over-the-counter (OTC) products, prescribed therapies, improper skin care, and procedures such as peels or laser therapy [1,[51][52][53][54].…”

Section: Lysatesmentioning

confidence: 99%

Dermocosmetics in the management of acne vulgaris. Recommendations of the Polish Dermatological Society. Part II

Zegarska,

Rudnicka,

Narbutt

et al. 2023

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Acne vulgaris is the most common dermatosis among adolescents, but it can also affect adults. Acne lesions located on the face cause discomfort and lead to impaired quality of life for many patients. Acne is a dermatological condition with multiple causes and clinical manifestations, as well as varying degrees of severity. Dermatological treatment alone does not always bring good therapeutic effects, and occasionally it may result in symptoms of skin irritation. Therefore, using appropriate dermocosmetics is crucial in managing the condition. Dermocosmetics play a potentially important role in minimizing the adverse effects of acne medications, providing a synergistic effect by addressing other acne-causing factors and/or enhancing the efficacy of other treatment modalities, and protecting the skin against the adverse impacts of the exposome. In cases of mild acne, dermocosmetics can be used in monotherapy as an alternative to acne medications or for maintenance therapy. It is also advisable to combine dermocosmetics with topical or systemic therapies to achieve a synergistic effect or to prevent and reduce drug-induced adverse reactions. Dermocosmetics have keratolytic and anti-inflammatory properties, regulate sebum production, and help maintain the balance of the skin's natural microbiome.

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Honey Phytochemicals: Bioactive Agents With Therapeutic Potential for Dermatological Disorders

McLoone,

Oladejo,

Kassym

et al. 2024

Phytotherapy Research

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Honey has been reported to have a range of biological activities including antimicrobial, immunomodulatory, and wound healing effects. Indeed, medical‐grade honey is currently used in hospitals for the clinical management of wound infections. Honey is also of scientific interest for its therapeutic effects on other dermatological disorders such as atopic dermatitis, rosacea, and skin cancer. Recent studies have uncovered that honey contains a range of phytochemicals including flavonoids, dicarboxylic acids, coumarins, and phenolic acids. In this review, PubMed was used to search the scientific literature on the biological properties of honey phytochemicals in relation to dermatological disorders and to evaluate their potential as bioactive agents, drugs, or cosmeceuticals for the treatment of skin disease. The review revealed that phytochemicals found in honey have antimicrobial, anti‐inflammatory, antiaging, antioxidant, anticancer, depigmenting, photoprotective, wound healing, and skin barrier enhancing properties. Although further high‐quality studies are required to establish clinical efficacy, these findings suggest that honey phytochemicals may have the potential to be used as bioactive agents for the management of a range of dermatological disorders including wounds, psoriasis, atopic dermatitis, vitiligo, rosacea, and skin cancer.

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Distinct skin microbiome modulation following different topical acne treatments in mild acne vulgaris patients: A randomized, investigator‐blinded exploratory study

Cited by 7 publications

References 36 publications

Adherence to treatment in dermatology: Literature review

Adherence to treatment in dermatology: Literature review

Dermocosmetics in the management of acne vulgaris. Recommendations of the Polish Dermatological Society. Part II

Honey Phytochemicals: Bioactive Agents With Therapeutic Potential for Dermatological Disorders

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