Distribution and evaluation of bone and soft tissue tumors operated in a tertiary care center

Abstract

Objective The aim of this study was to retrospectively evaluate the patients who were operated in our orthopedics and traumatology clinic with the suspection of bone and soft tissue tumors. Methods A total of 3133 patients (1146 (46.5%) female and 1318 (53.5%) male) who presented to our tertiary clinic from different regions of Turkey between January 2002 and July 2013 with the presumed diagnosis of bone and soft tissue tumors were analyzed according to age, gender, bone/soft tissue localization, tumoral localization, histopathological diagnosis, tumor size and incidence. Results Of all operated patients, 2464 (78%) were diagnosed with tumor, while non-tumoral causes were found in 669 (22%) patients. Of the cases diagnosed with tumor, 1139 were bone localized, 1004 soft tissue localized, and 321 metastasis. The most common benign bone tumors were osteochondroma (130, 20%), enchondroma (96, 15%), and simple bone cysts (90, 14%), while the most common malignant bone tumors were osteosarcoma (241, 44%), ewing's sarcoma (89, 16%), and chondrosarcoma (77, 14%); respectively. The most common benign soft tissue tumors were lipoma (141, 22%), giant cell tumors (108, 16%) and ganglion (107, 16%), while the most common malignant soft tissue tumors were liposarcoma (55, 16%), synovial sarcoma (53, 16%) and malignant mesenchymal tumors (45, 13%); respectively. Conclusion Musculoskeletal tumors are rare, but descriptive data in any region are important in order to reduce mortality and improve treatment. No significant difference was found between the data of our hospital regarding epidemiology of the musculoskeletal system tumors and those from the other regions around the world. Level of evidence Level IV, Therapeutic study.

Battle Against Musculoskeletal Tumors: Descriptive Data of Military Hospital Experience

“…Considering the prevalence of tumors, the most common benign soft tissue tumors were reported as lipoma, ganglion and giant cell tumor of tendon sheath, respectively, which was consistent with the literature (6)(7)(8). Whereas, the most common malignant soft tissue tumors have been reported as liposarcoma, pleomorphic cell sarcomas (malign fibrous histiocytomas), leiomyosarcomas, and synovial sarcomas, respectively, in a large referral population (6,10).…”

“…Regarding sex, male dominancy has been reported with a ratio of 1.5 for musculoskeletal tumors by Solooki et al's (13), whereas Solakoglu and Benzer (19) reported a male dominancy in bone tumors and female dominancy in soft tissue tumors which was supported by Ozturk et al (8). In the current study, musculoskeletal tumors have been found more common in males than females which could be contributed to the study population of male domination.…”

“…In a large population study of 20-year data, Yuceturk et al reported a total of 5658 musculoskeletal tumor cases to be aware of the specific rates in Aegean region (6), moreover Dabak et al published a 25year data of musculoskeletal tumors including 1925 cases from the central Black sea region (7). In a recent report, Ozturk et al experienced a total of 3,133 patients with the diagnosis of musculoskeletal tumors from different regions of Turkey in their tertiary care center (8). Among those previous reports, only one presents the data of musculoskeletal oncology experience in military personnel which is carried out in our hospital 26 years ago.…”

“…Malignant bone tumors accounted for 10% of all tumors, and 18% among all bone tumors, respectively, in this study. Among the malignant bone tumors, osteosarcoma was the most commonly encountered in the literature (6,8,9,14,16), however Sevimli reported chondrosarcoma as the most common malignant bone tumor in their locally designed studies (17). Bergovec et al reported chondrosarcoma to be the second (14,18).…”

Kemiğe nadir metastaz yapan tümörler

“…Patolojik kırık, büyük bir komplikasyondur ve litik iskelet lezyonları ile daha sık ilişkilidir. [11,12] Kemiğe metastaz yapabilen diğer tümörler arasında; melanom, nöroblastom, hepatosellüler karsinoma, karsinoid tümörler ve paraganglioma ile bazı solid tümörler bulunur, bu tür metastazların görülme sıklığı daha azdır.…”