Distribution of abo genotypes and allele frequencies in a korean population

Kang, Sung Ha; Fukumori, Yasuo; Ohnoki, Shiro; Shibata, Hirotoshi; Han, Kyou Sup; Nishimukai, Hiroaki; Okubo, Yasuto

doi:10.1007/bf02766955

Cited by 32 publications

(37 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In contrast, we found that the A102/O02 genotype was present in 14.9% of blood samples which was absent in the Kuwaiti population. Rare genotypes such as cis-AB01/O02 , cis-AB01/O01 , and cis-AB01/A102 were conspicuously absent in the current study with these latter alleles being detected among 13 different genotypes in the Korean population [8]. In addition, the cis-AB01 genotype has been reported in Japanese and Chinese populations [56].…”

Section: Discussionmentioning

confidence: 47%

“…This variation has been widely observed in many studies [56821222324]. In the majority of populations examined, the A101 and A102 alleles are common, whereas the O02 allele is predominant in the Saudi population.…”

Section: Discussionmentioning

confidence: 71%

“…Alleles such as O04 and A205 are found in the Han Chinese, and allele O06 is found in the Japanese [56]. Rare alleles such as cis-AB01 , cis-AB02 , and cis-AB06 are more frequently encountered in the Japanese, Korean, and Chinese populations [578]. …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Allelic variance amongABOblood group genotypes in a population from the western region of Saudi Arabia

et al. 2016

View full text Add to dashboard Cite

BackgroundCharacterization of the ABO blood group at the phenotype and genotype levels is clinically essential for transfusion, forensics, and population studies. This study elucidated ABO phenotypes and genotypes, and performed an evaluation of their distribution in individuals from the western region of Saudi Arabia.MethodsOne-hundred and seven samples underwent standard serological techniques for ABO blood group phenotype analysis. ABO alleles and genotypes were identified using multiplex polymerase chain reaction, and electrophoretic analysis was performed to evaluate the highly polymorphic ABO locus.ResultsA phenotype distribution of 37.4%, 30.8%, 24.3%, and 7.5% was found for blood groups O, A, B, and AB respectively in our study cohort. Genotype analysis identified 10 genotype combinations with the O01/O02 and A102/O02 genotypes being the most frequent with frequencies of 33.6% and 14.95%, respectively. Common genotypes such as A101/A101, A101/A102, A101/B101, B101/B101, and O01/O01 were not detected. Similarly, the rare genotypes, cis-AB01/O02, cis-AB01/O01, and cis-AB01/A102 were not found in our cohort. The most frequently observed allele was O02 (35.98%) followed by the A102 allele (17.76%). Furthermore, our findings are discussed in reference to ABO allele and genotype frequencies found in other ethnic groups.ConclusionThe study has a significant implication on the management of blood bank and transfusion services in Saudi Arabian patients.

show abstract

Section: Discussionmentioning

confidence: 47%

Section: Discussionmentioning

confidence: 71%

See 1 more Smart Citation

Allelic variance amongABOblood group genotypes in a population from the western region of Saudi Arabia

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Kang et al . reported the allelic frequencies of A101 , A102 , B101 , O01 and O02 in the Korean population to be 0·022, 0·209, 0·209, 0·360 and 0·200, respectively [8]. Our data agree with their findings, which suggest that the cis‐AB01/O01 and O02 genotypes should collectively be significantly more frequent than the cis‐AB01/A102 and cis‐AB01/B101 genotypes, and that the cis‐AB01/A102 genotype should be somewhat more frequent than the cis‐AB01/B101 genotype.…”

Section: Resultsmentioning

confidence: 99%

The serological and genetic basis of the cis‐AB blood group in Korea

et al. 2004

View full text Add to dashboard Cite

show abstract

“…Johnson and Hopkins ( 7) first demonstrated the presence of the genetic polymorphism of the ABO genes in an English population and subsequently the allele frequencies of the ABO genes in German ( 8), Swedish ( 9), and Korean ( 10) were reported. Our group ( 11) and Fukumori et al ( 12) previously described the genetic polymorphism of ABO alleles in a Japanese population.…”

mentioning

confidence: 99%

Polymorphism of the ABO blood group genes in Han, Kazak and Uygur populations in the Silk Route of northwestern China

et al. 2000

View full text Add to dashboard Cite

Genetic polymorphism in the ABO blood group gene of Han, Kazak and Uygur populations inhabiting the most northwestern part of China was investigated using polymerase chain reaction-based techniques. The present study enrolled 43 healthy unrelated Han, 37 Kazak and 59 Uygur volunteers. The allele in A1 blood group is distinguished A0101 and A0102 in difference of nucleotide position 467. The A0101 allele is more frequent in Caucasian and the A0102 allele is characteristic in Mongoloid. It must be notable that A0201 in the A2 group (with a single base deletion at nucleotides 1059 to 1061) which was characteristic of Caucasian was observed in Kazak and Uygur populations but not in Han. Further, 00201 (with no nucleotide deletion at 261 and three nucleotide differences), which is frequent in different races including Caucasian except for Mongoloid, was detected also in Kazak and Uygur populations. The frequencies of B0101 in Kazak, Uygur and Han were comparable to those of other Asian populations but higher than those of Caucasian populations. Collectively, these results reveal that the allele frequencies of Kazak and Uygur at the ABO blood group locus are an intermediate between those of Mongoloid and Caucasian, suggesting the admixed feature of Kazak and Uygur with Mongoloid and Caucasian.

show abstract

Distribution of abo genotypes and allele frequencies in a korean population

Abstract: SummaryThe genotypes of the ABO blood group system were investigated in Korean living in

Cited by 32 publications

References 13 publications

Allelic variance amongABOblood group genotypes in a population from the western region of Saudi Arabia

Allelic variance amongABOblood group genotypes in a population from the western region of Saudi Arabia

The serological and genetic basis of the cis‐AB blood group in Korea

Polymorphism of the ABO blood group genes in Han, Kazak and Uygur populations in the Silk Route of northwestern China

Contact Info

Product

Resources

About