Distributions of three transposable elements, P, 297, and copia, in natural populations of Drosophila melanogaster.

Yamaguchi, Osamu; Yamazaki, Tsuneyuki; Saigo, Kaoru; Mukai, Terumi; Robertson, Alan

doi:10.1266/jjg.62.205

Cited by 12 publications

(8 citation statements)

References 28 publications

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“…This opened the way for the further observation that TE movement and the resulting polymorphism could influence quantitative traits during artificial selection (Shrimpton et al 1990). While empirical data accumulated about various strains and populations (Yamaguchi et al 1987;Charlesworth et al 1992;Biémont et al 1994), theoretical approaches and simulations-the parameters of which involved transposition and excision rates, selection against the insertion of TEs, and effective population size-furnished useful models with which to confront the experimental data with some theoretical expectations (Charlesworth and Charlesworth 1983). …”

Section: Transposable Elements As Components Of Genetic Diversitymentioning

confidence: 99%

A Brief History of the Status of Transposable Elements: From Junk DNA to Major Players in Evolution

2010

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The idea that some genetic factors are able to move around chromosomes emerged more than 60 years ago when Barbara McClintock first suggested that such elements existed and had a major role in controlling gene expression and that they also have had a major influence in reshaping genomes in evolution. It was many years, however, before the accumulation of data and theories showed that this latter revolutionary idea was correct although, understandably, it fell far short of our present view of the significant influence of what are now known as ''transposable elements'' in evolution. In this article, I summarize the main events that influenced my thinking about transposable elements as a young scientist and the influence and role of these specific genomic elements in evolution over subsequent years. Today, we recognize that the findings about genomic changes affected by transposable elements have considerably altered our view of the ways in which genomes evolve and work.

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Section: Transposable Elements As Components Of Genetic Diversitymentioning

confidence: 99%

A Brief History of the Status of Transposable Elements: From Junk DNA to Major Players in Evolution

2010

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“…This sequence is spread over the genome in dozens of copies, some of which are transcriptionally active (Yamaguchi et al, 1987). In fact, it is contained in numerous BDGP ESTs and genomic P1 phage subclones.…”

Section: Ltr Of Copia-like Element 297mentioning

confidence: 99%

TheDrosophila melanogaster60A Chromosomal Division Is Extremely Dense with Functional Genes: Their Sequences, Genomic Organization, and Expression

et al. 1999

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“…Such results have not been reported for other elements, however (Ronsseray & Anxolabrhrre, 1986), although insertions in ectopic fibers can often be observed. Hence the copy number distribution of most elements is now considered to be usually Poisson (Charlesworth & Lapid, 1989) with low frequencies at individual chromosomal sites, although the variance of the P and 297 element copy numbers in populations analysed by Yamaguchi et al (1987) were highly significantly greater than those expected under the Poisson distribution. The distribution of Ac-like sequences in inbred maize also does not fit the expected Poisson distribution.…”

Section: The Regions Of Insertionmentioning

confidence: 99%

Population genetics of transposable DNA elements

Biémont

1992

Genetica

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This paper is an attempt to bring together the various, dispersed data published in the literature on insertion polymorphism of transposable elements from various kinds of populations (natural populations, laboratory strains, isofemale and inbred lines). Although the results deal mainly with Drosophila, data on other organisms have been incorporated when necessary to illustrate the discussion. The data pertinent to the regions of insertion, the rates of transposition and excision, the copy number regulation, and the degree of heterozygosity were analysed in order to be confronted with the speculations made with various theoretical models of population biology of transposable elements. The parameters of these models are very sensitive to the values of the transposable element characteristics estimated on populations, and according to the difficulties of these estimations (population not at equilibrium, particular mutations used to estimate the transposition and excision rates, trouble with the in situ technique used to localize the insertions, undesired mobilization of TEs in crosses, spontaneous genome resetting, environmental effects, etc.) it cannot be decided accurately which model better accounts for the population dynamics of these TEs. Tendencies, however, emerge in Drosophila: the copia element shows evidence for deficiency of insertions on the X chromosomes, a result consistent with selection against mutational effects of copia insertions; the P element repartition does not significantly deviate from the neutral assumption, in spite of a systematic copy number of insertions higher on the X than on the autosomes. Data on other elements support either the neutral model of TE containment, neither of the two models, or both. Prudence in conclusion should then be de rigueur when dealing with such kind of data. Finally the potential roles of TEs in population adaptation and evolution are discussed.

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Distributions of three transposable elements, P, 297, and copia, in natural populations of Drosophila melanogaster.

Cited by 12 publications

References 28 publications

A Brief History of the Status of Transposable Elements: From Junk DNA to Major Players in Evolution

A Brief History of the Status of Transposable Elements: From Junk DNA to Major Players in Evolution

TheDrosophila melanogaster60A Chromosomal Division Is Extremely Dense with Functional Genes: Their Sequences, Genomic Organization, and Expression

Population genetics of transposable DNA elements

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