DLFFNet: A new dynamical local feature fusion network for automatic aortic valve calcification recognition using echocardiography

Tang, Lingzhi; Wang, Xueqi; Yang, Jinzhu; Wang, Yonghuai; Qu, Mingjun; Li, HongHe

doi:10.1016/j.cmpb.2023.107882

Cited by 5 publications

(1 citation statement)

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“…An increased coronary artery calcium score (CAC) correlates in fact with the severity of coronary artery disease (CAD) [ 6 ] and an increased rate of CAC progression correlates with adverse cardiac events [ 7 ]. Traditionally considered as an aging by product, VC is now recognized as an actively regulated process akin to bone mineralization, serving as both a cardiovascular risk marker and a treatment target, with ongoing development of detection methods to enhance its clinical utility [ 8 , 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

Mechanisms of Cardiovascular Calcification and Experimental Models: Impact of Vitamin K Antagonists

Siracusa,

Carino,

Carabetta

et al. 2024

JCM

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Cardiovascular calcification is a multifactorial and complex process involving an array of molecular mechanisms eventually leading to calcium deposition within the arterial walls. This process increases arterial stiffness, decreases elasticity, influences shear stress events and is related to an increased risk of morbidity and mortality associated with cardiovascular disease. In numerous in vivo and in vitro models, warfarin therapy has been shown to cause vascular calcification in the arterial wall. However, the exact mechanisms of calcification formation with warfarin remain largely unknown, although several molecular pathways have been identified. Circulating miRNA have been evaluated as biomarkers for a wide range of cardiovascular diseases, but their exact role in cardiovascular calcification is limited. This review aims to describe the current state-of-the-art research on the impact of warfarin treatment on the development of vascular calcification and to highlight potential molecular targets, including microRNA, within the implicated pathways.

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