DNA cleavage protecting activity and in vitro antioxidant potential of aqueous extract from fresh stems ofRheum ribes

Influence of extraction method on antioxidant properties of Rheum ribes root extract

“…The results were expressed as gallic acid equivalent equivalents (GAE, mg of GA per 1 mL sample) [8,9]. The calibration equation for GA is A = 0.0019x + 0.0095 (R 2 = 0.9996).…”

“…There are many assays in vitro used to measure the antioxidant effect of Rheum ribes extract [1,[4][5][6][7][8]. Some authors reported the antioxidant properties of Rheum ribes extracts [1,[9][10][11].…”

“…The antioxidative properties were examined by using spectrophotometric methods, i.e. 2,2-diphenyl-2picryl-hydrazyl free radical scavenging (DPPH) and Ferric Reducing Antioxidant Power (FRAP) assays [9]. In addition, Folin-Ciocalteu modified method was used for determining the total phenolic content [10][11][12].…”

Protective effect of hydroalcoholic Rheum ribes L. extract in male rat model of lead acetate-induced nephrotoxicity

“…Treatment with R. ribes extract at 400-mg/kg concentration significantly increased serum antioxidant capacity in the rat exposed to lead acetate. While antioxidant and anti-inflammatory properties of this extract have been demonstrated (6,19,20), it can be argued that R. ribes extract prevents cell damage and dysfunction through decreasing inflammatory cytokines, inhibiting free radicals and reactive oxygen species (ROS), and increasing tissue and serum antioxidant capacity. It is worth mentioning that in our study, lead acetate did not decrease antioxidant capacity but R. ribes extract increased it.…”

Rheum Ribes L.'nin etanol ekstrelerinin malign melanoma hücreleri üzerine anti-kanser etkinliğinin araştırılması

“…Halk arasında birçok hastalığın tedavisinde kullanılmış olması bu bitki üzerine bilimsel çalışmaları cazip hale getirmiştir. Rheum ribes L.'in antioksidan, anti-bakteriyel, anti-trikomonas, anti-viral, anti-fungal, anti-diyabetik, anti-dayareik, anti-hiperlipidemik özellikleri üzerine çok sayıda çalışma yapılmıştır (5)(6)(7)(8)(9)(10)(11)(12)(13)(14). Ayrıca Alzheimer hastalığının hafif ve orta şiddetteki vakalarında kullanılan asetil kolin esteraz inhibitörleri gibi etki gösterdiğini ortaya koyan çalışmalar da mevcuttur (15).…”