DNA hydrogels combined with microfluidic chips for melamine detection

Chen, Ruipeng; Hou, Yayi; Qin, Yingkai; Li, Shuang; Yang, Shiping; Gao, Zhixian

doi:10.1016/j.aca.2022.340312

Cited by 30 publications

(12 citation statements)

References 29 publications

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“…According to the method used in our previous research to prepare DNA hydrogel, 33 the steps were as follows: first, linear-chain polyacrylamide DNA polymers were prepared. LA or LB were mixed with 2.5% acrylamide and fully shaken, then vacuum deoxidization was performed at 37 °C for 6 min.…”

Section: Methodsmentioning

confidence: 99%

Exo I signal amplification of a DNA hydrogel film combined with capillary self-driven action for EpCAM detection

Li,

Wang,

Lin

et al. 2023

Analyst

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Section: Methodsmentioning

confidence: 99%

Exo I signal amplification of a DNA hydrogel film combined with capillary self-driven action for EpCAM detection

Li,

Wang,

Lin

et al. 2023

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“…Although it is an industrial raw material, MEL is often used illegally to increase the apparent protein content of dairy products and animal feed due to its high nitrogen content. Wang et al [ 169 ] combined stimulus-responsive DNA hydrogels with microfluidic chips to design a colorimetric biosensor. The DNA hydrogel can block the liquid channel; however, when MEL is present, the hydrogel collapses and liquid flows into the detection zone, allowing quantitative analysis based on the color change in the released AuNPs.…”

Section: Stimulus-responsive Dna Hydrogel Biosensors For Food Safety ...mentioning

confidence: 99%

Stimulus-Responsive DNA Hydrogel Biosensors for Food Safety Detection

Wang

Lai

et al. 2023

Biosensors

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Food safety has always been a major global challenge to human health and the effective detection of harmful substances in food can reduce the risk to human health. However, the food industry has been plagued by a lack of effective and sensitive safety monitoring methods due to the tension between the cost and effectiveness of monitoring. DNA-based hydrogels combine the advantages of biocompatibility, programmability, the molecular recognition of DNA molecules, and the hydrophilicity of hydrogels, making them a hotspot in the research field of new nanomaterials. The stimulus response property greatly broadens the function and application range of DNA hydrogel. In recent years, DNA hydrogels based on stimulus-responsive mechanisms have been widely applied in the field of biosensing for the detection of a variety of target substances, including various food contaminants. In this review, we describe the recent advances in the preparation of stimuli-responsive DNA hydrogels, highlighting the progress of its application in food safety detection. Finally, we also discuss the challenges and future application of stimulus-responsive DNA hydrogels.

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“…After each test, the microchannel was washed with isopropanol to remove residual liquids and then dried. The extraction efficiency (EE(%)) 1) and the overall volumetric mass transfer coefficient (k L a) were used to characterize the microchannel mass transfer performance. The relationships are given in Eqs.…”

Section: Diclofenac Liquid-liquid Extraction In Y-junction Microchannelmentioning

confidence: 99%

“…Inkjet printers, portable blood analyzers, DNA and protein chips, lab-on-a-chip, and microanalysis systems are examples of microfluidic devices and systems [1][2][3][4][5][6][7][8][9]. Using microfluidics in operational units has various advantages.…”

Section: Introductionmentioning

confidence: 99%

Diclofenac Sodium Solvent Extraction Based on Two‐Phase Flow Patterns

2022

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Diclofenac (DF) solvent extraction using tetra‐n‐butyl ammonium bromide (TBAB) in Y‐type microfluidic junctions with liquid‐liquid two‐phase flow patterns was investigated. The hydrodynamics of parallel, slug, and droplet flows were examined. The results indicated that the extraction efficiency decreased with increasing velocity. At QO/QA greater than 2.5, the flow pattern was converted from slug into droplet flow, and due to the enlargement of the specific surface area, the extraction efficiency increased. Slug flow provided an equilibrium extraction efficiency of 99.2 %. The overall volumetric mass transfer coefficient at different lengths and widths was evaluated. The best mass transfer performance occurred in microchannels with a length of 9 cm and a width of 400 µm.

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DNA hydrogels combined with microfluidic chips for melamine detection

Cited by 30 publications

References 29 publications

Exo I signal amplification of a DNA hydrogel film combined with capillary self-driven action for EpCAM detection

Exo I signal amplification of a DNA hydrogel film combined with capillary self-driven action for EpCAM detection

Stimulus-Responsive DNA Hydrogel Biosensors for Food Safety Detection

Diclofenac Sodium Solvent Extraction Based on Two‐Phase Flow Patterns

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