DNA methylation changes in Oct3/4 gene promoter region of HUCB-NSC in response to neural differentiation

Heavy Metals Contamination Through Industrial Effluent to Irrigation Water in Gadoon Amazai (Swabi) and Hayatabad (Peshawar) Pakistan

“…The total daily intake of Co is variable and may be as much as 1 mg, but almost all will pass through the body unabsorbed, except that in vitamin B 12 [24]. Plants also need this metal in the form of colbalmin for the regulation of DNA synthesis during cell division [25]. In spite of the beneficial effects of cobalt for humans, its high concentrations may be toxic to human health.…”

“…In spite of the beneficial effects of cobalt for humans, its high concentrations may be toxic to human health. Breathing in air containing too high concentrations of Co may lead to serious lung problems, such as asthma and pneumonia [25]. Several adverse effects of Co have been demonstrated in plants [26][27].…”

“…The deficiency of Fein the body may be compensated with the use of vitamin C tablets, as this vitamin reduces tertiary Fe to binary Fe. Fe is a central component of haemoglobin which transports oxygen from lungs to other body parts and CO 2 back to the lungs [25]. In spite of the importance in the body, exceeded amount of Fe may cause a number of problems such as bone marrow, damage of vital organs like pancreas, liver, spleen and the heart, when taken more than 200 ppm in drinking water.…”