DNA-templated copper nanocluster: A robust and universal fluorescence switch for bleomycin assay

An ATMND/SGI based three-way junction ratiometric fluorescent probe for rapid and sensitive detection of bleomycin

“…To date, various sensitive methods for BLM detection have been developed, such as high-performance liquid chromatography (HPLC), 9 electrochemical assay, 10 electrochemiluminescence assay, 11 photoelectrochemical (PEC) assay, 12 colorimetrical assay 13 and fluorescence analysis. 14–16 Notably, the fluorescence (FL) method has garnered significant attention due to its simple sample pretreatment, facile instrument operation, low cost, rapid response and high sensitivity. In addition, the BLM–Fe( ii ) complex has the unique ability to selective cleave DNA strands by oxidizing the deoxyribose moiety in the presence of oxygen.…”