Advances in Fisheries Biotechnology 2021
DOI: 10.1007/978-981-16-3215-0_19
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DNA Vaccines for Fish

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“…DNA motifs and mRNA transcripts express immunogenic proteins in fish that simulate infection by intracellular pathogens and allow the presentation of exogenous antigenic peptides on the APC surface via major histocompatibility complex (MHC) class I. Subsequently, APC at the site of administration may trigger immune cells ( 314 , 315 ). Antigen-presenting cells can also absorb soluble antigens released from transfected myoblasts (or other cells) or in the presence of antigenic apoptotic vesicles, delivered to MHC class II molecules on the cell surface.…”
Section: Mechanism Of Aquatic Vaccinesmentioning
confidence: 99%
“…DNA motifs and mRNA transcripts express immunogenic proteins in fish that simulate infection by intracellular pathogens and allow the presentation of exogenous antigenic peptides on the APC surface via major histocompatibility complex (MHC) class I. Subsequently, APC at the site of administration may trigger immune cells ( 314 , 315 ). Antigen-presenting cells can also absorb soluble antigens released from transfected myoblasts (or other cells) or in the presence of antigenic apoptotic vesicles, delivered to MHC class II molecules on the cell surface.…”
Section: Mechanism Of Aquatic Vaccinesmentioning
confidence: 99%