Do astronauts get postural tachycardia syndrome? And other updates on recent autonomic research

Miglis, Mitchell G.; Muppidi, Srikanth

doi:10.1007/s10286-019-00613-z

Cited by 1 publication

(1 citation statement)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The model presented here represents a healthy adult male astronaut and does not include any gender effects. With increasing numbers of female astronauts experiencing long-duration spaceflight, a logical extension of this work would be to include a gendered analysis which may provide further insights into cardiovascular deconditioning of spaceflight as well other disorders of orthostatic intolerance such as postural tachycardia syndrome 47 .…”

Section: Discussionmentioning

confidence: 99%

Computational modeling of orthostatic intolerance for travel to Mars

et al. 2022

View full text Add to dashboard Cite

Astronauts in a microgravity environment will experience significant changes in their cardiopulmonary system. Up until now, there has always been the reassurance that they have real-time contact with experts on Earth. Mars crew however will have gaps in their communication of 20 min or more. In silico experiments are therefore needed to assess fitness to fly for those on future space flights to Mars. In this study, we present an open-source controlled lumped mathematical model of the cardiopulmonary system that is able simulate the short-term adaptations of key hemodynamic parameters to an active stand test after being exposed to microgravity. The presented model is capable of adequately simulating key cardiovascular hemodynamic changes—over a short time frame—during a stand test after prolonged spaceflight under different gravitational conditions and fluid loading conditions. This model can form the basis for further exploration of the ability of the human cardiovascular system to withstand long-duration space flight and life on Mars.

show abstract

Section: Discussionmentioning

confidence: 99%