Dodonaea viscosa Leaf Extract Assisted Synthesis of Gold Nanoparticles: Characterization and Cytotoxicity Against A549 NSCLC Cancer Cells

Anandan, M.; Prabu, H. Gurumallesh

doi:10.1007/s10904-018-0799-6

Cited by 15 publications

(9 citation statements)

References 39 publications

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“…Mounting reports shows that constant aggravation is one of the [20]. In expansion, gold nanoparticles arranged plant separate showed huge little cell cellular breakdown in the lung's cells [21]. In another examination, ethanolic concentrate of D. viscosa showed stamped cytotoxicity against HT-29 human colon malignancy cell line [22].…”

Section: Discussionmentioning

confidence: 99%

“…Past examinations show that Kaempferol, a generally circulated flavonoid present in D.viscosa displayed apodosis intervened malignant growth cell passing was explored for the blockage of apoptotic cell death [20]. In expansion, gold nanoparticles arranged from D. viscosa plant separate showed huge cytotoxic action against non-little cell cellular breakdown in the lung's cells [21]. examination, ethanolic concentrate of showed stamped cytotoxicity against HT human colon malignancy cell line [22].…”

Section: Discussionmentioning

confidence: 99%

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In-vitro Anti-Cancer and Anti-Inflammatory Screening of Dodonaea viscosa

Ramkumar¹,

Periyasamy²,

Venkatraman³

et al. 2021

JPRI

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Background: The current investigation was done to assess the in vitro anticancer property of Dodonaea viscosa (D. viscosa) in three malignant growth cell lines and mitigating impact in RAW 264.7 macrophages. Methods: The hydroalcoholic remove D. viscosa was ready and tried against HCT-116 colon malignancy, MCF-7 bosom disease HeLa cervical disease cell lines. The cytotoxicity of concentrate was affirmed by MTT cheeky. The calming movement of concentrate was assessed utilizing LPS invigorated RAW 264.7 macrophages and the degree of incendiary middle people was estimated. Results: The anticancer impact of D. viscosa onHCT-116, MCF-7 and HeLa cell line with the IC50 worth of 60.43 ± 0.76 μg/ml,75.26 ± 0.45 μg/ml and 72.12 ± 0.87μg/ml individually. Further, in LPS stimulatedRAW264.7 macrophage cells, treatment with D. viscosa extract altogether decreased the raised level of NO, TNF-α and PGE2. Conclusion: This examination gave the proof to D. viscosa an anticancer and mitigating specialist. Further bioactive confinement and atomic examinations are needed to prove the impact of plant remove.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

In-vitro Anti-Cancer and Anti-Inflammatory Screening of Dodonaea viscosa

Ramkumar¹,

Periyasamy²,

Venkatraman³

et al. 2021

JPRI

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“…There were several studies related to cytotoxicity of D. viscosa, an in-vitro study showed that the synthesized AuNPs (gold nanoparticles) using Dodonaea viscosa leaf extract inhibited the growth of A549 NSCLC cells (adenocarcinomic human alveolar basal epithelial cells), being the most active the methanol extract with the IC 50 values of 4.0 µg/ml 22 . Dodoneasides A and B isolated from the ethanol extract of D. viscosa roots showed antiproliferative activity against the A2780 human ovarian cancer cell line 23 .…”

Section: Discussionmentioning

confidence: 99%

Dodonaea viscosa Jacq: A Medicinal Plant with Cytotoxic Effect on Colon Cancer Cell Line (HT-29)

Herrera-Calderon¹,

Rahman²,

Peña-Rojas³

et al. 2020

J Pure Appl Microbiol

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Dodonaea viscosa (Family: Sapindaceae) is a medicinal plant that has been used as anti-rheumatic and bone pain in Peru as a folk remedy. Ethanol extract obtained from D. viscosa leaves was partitioned as n-hexane fraction; chloroform fraction; ethyl acetate fraction; n-butanol fraction and aqueous fraction. Phytoconstituents from D. viscosa leaves were evaluated by using chemical reagents to identify the presence of each phytochemical. In addition, a cytotoxic effect was determined by the Sulforhodamine B (SRB) test. The results showed that the ethanol extract and ethyl acetate fraction of leaves had the highest variety of phytoconstituents. The ethanol extrac of leaves exhibited a major inhibitory effect compared to different fractions in human colon cancer cells (HT-29). From these assays, it is concluded that D. viscosa does not possess any detectable cytotoxic effect on epidermal cells from mouse (3T3), and a slight cytotoxic effect against HT-29 tumor cells compared to 5-FU. This species could appear like a good source of herbal medicine in colorectal cancer disease.

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“…SAED has been used in the analysis of biopolymers to obtain information regarding their crystalline structure [184][185][186][187]. However, SAED is proven to be a more prominent technique in the analysis of the biopolymer-assisted synthesis of metallic nanoparticles [22,23,[188][189][190][191]; SAED analysis of biopolymer gum guar capped silver nanoparticles revealed information about the crystalline structure of the nanoparticles. The diffraction pattern ( Figure 12) consisted of concentric rings with bright dots, which suggests that the synthesized particles are highly crystalline in nature; the rings were further assigned to (111), (200), (220), and (311) planes of the face-centered cubic structure of the particles [192].…”

Section: Transmission Electron Microscopymentioning

confidence: 99%

Microscopic Techniques for the Analysis of Micro and Nanostructures of Biopolymers and Their Derivatives

et al. 2020

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Natural biopolymers, a class of materials extracted from renewable sources, is garnering interest due to growing concerns over environmental safety; biopolymers have the advantage of biocompatibility and biodegradability, an imperative requirement. The synthesis of nanoparticles and nanofibers from biopolymers provides a green platform relative to the conventional methods that use hazardous chemicals. However, it is challenging to characterize these nanoparticles and fibers due to the variation in size, shape, and morphology. In order to evaluate these properties, microscopic techniques such as optical microscopy, atomic force microscopy (AFM), and transmission electron microscopy (TEM) are essential. With the advent of new biopolymer systems, it is necessary to obtain insights into the fundamental structures of these systems to determine their structural, physical, and morphological properties, which play a vital role in defining their performance and applications. Microscopic techniques perform a decisive role in revealing intricate details, which assists in the appraisal of microstructure, surface morphology, chemical composition, and interfacial properties. This review highlights the significance of various microscopic techniques incorporating the literature details that help characterize biopolymers and their derivatives.

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Dodonaea viscosa Leaf Extract Assisted Synthesis of Gold Nanoparticles: Characterization and Cytotoxicity Against A549 NSCLC Cancer Cells

Cited by 15 publications

References 39 publications

In-vitro Anti-Cancer and Anti-Inflammatory Screening of Dodonaea viscosa

In-vitro Anti-Cancer and Anti-Inflammatory Screening of Dodonaea viscosa

Dodonaea viscosa Jacq: A Medicinal Plant with Cytotoxic Effect on Colon Cancer Cell Line (HT-29)

Microscopic Techniques for the Analysis of Micro and Nanostructures of Biopolymers and Their Derivatives

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