Does coffee affect bowel recovery following minimally invasive colorectal operations? A three-armed randomized controlled trial

Nasseri, Yosef; Kasheri, Eli; Oka, Kimberly; Zhu, Ruoyan; Smiley, Abbas; Cohen, Jason; Ellenhorn, Joshua D. I.; Barnajian, Moshe

doi:10.1007/s00384-023-04494-7

Cited by 4 publications

(21 citation statements)

References 27 publications

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“…Six of the included studies were RCTs [ 20 – 23 , 34 , 36 ], while two studies did not use randomization [ 35 , 37 ]. Five studies originated from Europe [ 20 , 22 , 34 – 36 ], two from the Middle East [ 21 , 37 ], and one from North America [ 23 ]. In all but one study [ 34 ], patients were assigned on a single-center basis.…”

Section: Resultsmentioning

confidence: 99%

“…In all studies, caffeinated drinks (single dose of 100–150 ml) were administered three times daily from the same day of surgery until the second postoperative day. Interestingly, two studies compared caffeinated coffee with decaffeinated coffee drink [ 20 , 23 ]. In both study groups the majority of cases were performed minimally-invasively (caffeinated drinks: 81.47%, control: 82.41%).…”

Section: Resultsmentioning

confidence: 99%

“…Only left-sided resections were reported in the study by Dulskas et al [ 20 ]. In addition, four patients underwent rectopexy procedure [ 23 ]. Adherence to fast-track protocols was mentioned in four studies [ 20 , 23 , 34 , 36 ].…”

Section: Resultsmentioning

confidence: 99%

“…In addition, four patients underwent rectopexy procedure [ 23 ]. Adherence to fast-track protocols was mentioned in four studies [ 20 , 23 , 34 , 36 ]. A thoracic epidural catheter was used for analgesia in two studies [ 22 , 34 ].…”

Section: Resultsmentioning

confidence: 99%

“…colorectal resection NS Yes Caffeine (100/200 mg)/3× daily, dispensed into capsules with corn starch Corn starch capsules Same day of surgery Bildirici et al [ 37 ] 2022 Turkey Nov 2018–Jun 2019 Single-center, prospective, non-randomized 60 (ITT)/51 (PP) Elective lap. colorectal surgery NS NS Coffee (100 ml)/3× daily, (instant coffee) Water (100 ml) Same day of surgery Nasseri et al [ 23 ] 2023 USA Dec 2016–Jun 2021 Single-center, prospective, RCT 102 (ITT)/99 (PP) Elective minimally-invasive colorectal surgery Yes No Caffeinated coffee (116 ml)/3× daily Decaffeinated coffee 3x daily (116 ml), warm water (116 ml) POD 1 ITT intention-to-treat, NS not stated, POD postoperative day, PP per-protocol, RCT randomized controlled trial …”

Section: Resultsmentioning

confidence: 99%

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Caffeine intake enhances bowel recovery after colorectal surgery: a meta-analysis of randomized and non-randomized studies

Vaghiri,

Prassas,

David

et al. 2024

Updates Surg

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Postoperative ileus (POI) after colorectal surgery is a major problem that affects both patient recovery and hospital costs highlighting the importance of preventive strategies. Therefore, we aimed to perform a systematic analysis of the effects of postoperative caffeine consumption on bowel recovery and surgical morbidity after colorectal surgery. A comprehensive literature search was conducted through September 2023 for randomized and non-randomized trials comparing the effect of caffeinated versus non-caffeinated drinks on POI by evaluating bowel movement resumption, time to first flatus and solid food intake, and length of hospital stay (LOS). Secondary outcome analysis included postoperative morbidity in both groups. After data extraction and inclusion in a meta-analysis, odds ratios (ORs) for dichotomous variables and standardized mean differences (SMDs) for continuous outcomes with 95% confidence intervals (CIs) were calculated. Subgroup analyses were performed in cases of substantial heterogeneity. Six randomized and two non-randomized trials with a total of 610 patients were included in the meta-analysis. Caffeine intake significantly reduced time to first bowel movement [SMD −0.39, (95% CI −0.66 to −0.12), p = 0.005] and time to first solid food intake [SMD −0.41, (95% CI −0.79 to −0.04), p = 0.03] in elective laparoscopic colorectal surgery, while time to first flatus, LOS, and the secondary outcomes did not differ significantly. Postoperative caffeine consumption may be a reasonable strategy to prevent POI after elective colorectal surgery. However, larger randomized controlled trials (RCTs) with homogeneous study protocols, especially regarding the dosage form of caffeine and coffee, are needed.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Caffeine intake enhances bowel recovery after colorectal surgery: a meta-analysis of randomized and non-randomized studies

Vaghiri,

Prassas,

David

et al. 2024

Updates Surg

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Global research trends in postoperative ileus from 2011 to 2023: A Scientometric study

Zhou,

Yin,

Sun

et al. 2024

Preprint

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Objective To explore the current status, trends, and frontiers of POI research from 2011 to the present based on bibliometric analysis. Methods Publications published on POI research from 2011 to 2023 were retrieved on June 1, 2023, from the Web of Science Core Collection. CiteSpace 6.2.R2 and VOSviewer were used to conduct bibliometric visualization. Results In total, 778 POI records published from 2011 to 2023 were retrieved. Over the past few decades, the annual cumulative number of related articles has linearly increased, with China and the United States of America (USA) contributing prominently. All the publications were from 59 countries and territories. China and the University of Bonn were the top contributing country and institution, respectively. Neurogastroenterology & Motility was the most prolific journal. The Journal of Gastrointestinal Surgery had the highest number of citations. Wehner Sven was the most productive author. Burst keywords (e.g., colon, prolonged ileus, acupuncture, paralytic ileus, pathophysiology, rectal cancer, gastrointestinal function, risk) and a series of reference citation bursts provided evidence for the research frontiers in recent years. Conclusions This study demonstrates trends in the published literature on POI and provides new insights for researchers. It emphasizes the importance of multidisciplinary cooperation in the development of this field.

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Global research trends in postoperative ileus from 2011 to 2023: A scientometric study

Zhou,

Yin,

Sun

et al. 2024

World J Gastrointest Surg

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BACKGROUND Postoperative ileus (POI) is a common complication after abdominal surgery with high morbidity, which hinders patient recovery, prolongs hospitalization, and increases healthcare costs. Therefore, POI has become a global public health challenge. POI triggering is multifactorial. Autonomic and hormonal mechanisms are generally involved in POI pathogenesis. Recent studies have shown that beta adrenergic signaling of enteric glia is a POI trigger. Currently, the status quo, trends, and frontiers of global research on POI remain unclear. AIM To explore the current status, trends, and frontiers of POI research from 2011 to the present based on bibliometric analysis. METHODS Publications published on POI research from 2011 to 2023 were retrieved on June 1, 2023, from the Web of Science Core Collection. CiteSpace 6.2.R2 and VOSviewer were used to conduct bibliometric visualization. RESULTS In total, 778 POI records published from 2011 to 2023 were retrieved. Over the past few decades, the annual cumulative number of related articles has linearly increased, with China and the United States of America contributing prominently. All publications were from 59 countries and territories. China and the University of Bonn were the top contributing country and institution, respectively. Neurogastroenterology & Motility was the most prolific journal. The Journal of Gastrointestinal Surgery had the highest number of citations. Wehner Sven was the most productive author. Burst keywords (e.g. , colon, prolonged ileus, acupuncture, paralytic ileus, pathophysiology, rectal cancer, gastrointestinal function, risk) and a series of reference citation bursts provided evidence for the research frontiers in recent years. CONCLUSION This study demonstrates trends in the published literature on POI and provides new insights for researchers. It emphasizes the importance of multidisciplinary cooperation in the development of this field.

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Does coffee affect bowel recovery following minimally invasive colorectal operations? A three-armed randomized controlled trial

Cited by 4 publications

References 27 publications

Caffeine intake enhances bowel recovery after colorectal surgery: a meta-analysis of randomized and non-randomized studies

Caffeine intake enhances bowel recovery after colorectal surgery: a meta-analysis of randomized and non-randomized studies

Global research trends in postoperative ileus from 2011 to 2023: A Scientometric study

Global research trends in postoperative ileus from 2011 to 2023: A scientometric study

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