Does Contrast Medium Administration in Organ Donors Affect Early Kidney Graft Function?

Große, Katharina; Brauer, Brian C.; Küçük, Onur; Krüger, R.; Polster, F.; Grauhan, O.; Wesslau, C

doi:10.1016/j.transproceed.2006.01.034

Cited by 17 publications

(8 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…No significant increase in the prevalence of delayed graft function or reduction in graft survival has been associated with perimortem donor contrast studies (257,269,270).…”

Section: Can a Kidney Be Accepted From A Donor Who Has Received IV Comentioning

confidence: 98%

“…Cardiac catheterization provides information regarding wall motion. Importantly, the administration of contrast media in coronary angiography has not been associated with impairment of donor kidney function, especially if the usual recommendations to diminish this risk are observed (257). The expense of coronary angiography is offset by the potential to obviate unnecessary mobilization of transport teams and unnecessary travel (258).…”

Section: Recommendationmentioning

confidence: 99%

See 1 more Smart Citation

Management of the Potential Organ Donor in the ICU

Kotloff

Blosser

Fulda

et al. 2015

Critical Care Medicine

280

150

View full text Add to dashboard Cite

This document was developed through the collaborative efforts of the Society of Critical Care Medicine, the American College of Chest Physicians, and the Association of Organ Procurement Organizations. Under the auspices of these societies, a multidisciplinary, multi-institutional task force was convened, incorporating expertise in critical care medicine, organ donor management, and transplantation. Members of the task force were divided into 13 subcommittees, each focused on one of the following general or organ-specific areas: death determination using neurologic criteria, donation after circulatory death determination, authorization process, general contraindications to donation, hemodynamic management, endocrine dysfunction and hormone replacement therapy, pediatric donor management, cardiac donation, lung donation, liver donation, kidney donation, small bowel donation, and pancreas donation. Subcommittees were charged with generating a series of management-related questions related to their topic. For each question, subcommittees provided a summary of relevant literature and specific recommendations. The specific recommendations were approved by all members of the task force and then assembled into a complete document. Because the available literature was overwhelmingly comprised of observational studies and case series, representing low-quality evidence, a decision was made that the document would assume the form of a consensus statement rather than a formally graded guideline. The goal of this document is to provide critical care practitioners with essential information and practical recommendations related to management of the potential organ donor, based on the available literature and expert consensus.

show abstract

“…No significant increase in the prevalence of delayed graft function or reduction in graft survival has been associated with perimortem donor contrast studies (257,269,270).…”

Section: Can a Kidney Be Accepted From A Donor Who Has Received IV Comentioning

confidence: 98%

Section: Recommendationmentioning

confidence: 99%

Management of the Potential Organ Donor in the ICU

Kotloff

Blosser

Fulda

et al. 2015

Critical Care Medicine

280

150

View full text Add to dashboard Cite

show abstract

“…Grosse et al. found that CA or left ventriculography did not influence DGF rate . This study was conducted in a small cohort of 36 donors.…”

Section: Discussionmentioning

confidence: 82%

Impact of donor coronary angiography on kidney transplantation outcomes

Lesouhaitier

Legeai

Savoye

et al. 2018

Clinical Transplantation

View full text Add to dashboard Cite

Coronary angiography (CA) is the gold standard evaluation of coronary artery disease in potential multi-organ donors. This use of iodinated contrast media could lead to contrast-induced acute kidney injury and consequently to delayed graft function (DGF). All patients in France who received a kidney from a 45-70-year-old donor without medical contraindication for cardiac donation and with at least one cardiovascular risk factor were included. Recipients of preemptive kidney transplant or multi-organ transplant, or who died within the first 8 days post-transplantation were excluded. Data were obtained from CRISTAL database. From March 2012 to June 2014, 892 kidneys from 483 donors were transplanted. DGF was reported in 38.9% of the 375 kidney recipients grafted with a kidney from the 217 donors who had CA and in 45.5% of the 440 kidney recipients who received a kidney from the 257 donors without CA. Multivariate analysis showed that CA or repeated injection of iodinated contrast media did not influence the risk of DGF. CA did not increase the risk of primary non-function, the duration of DGF or post-transplantation hospital stay and did not affect the graft function at 1 year. Evaluation of potential multi-organ donors with CA does not affect kidney graft outcomes.

show abstract

“…We could not find any literature specific for heart donors. However, a similar question was posed for kidney donors . The authors conclude that the administration of contrast medium had no influence on renal function at 3 or 6 months after transplantation, so in conclusion, fears that donor kidneys might be harmed by contrast medium appeared to be unfounded.…”

Section: Discussionmentioning

confidence: 99%

Intractable coronary fibromuscular dysplasia leading to end‐stage heart failure and fatal heart transplantation

et al. 2020

View full text Add to dashboard Cite

Coronary fibromuscular dysplasia is uncommon, and even rarer its unstable and recurrent course. We present the unique case of a 52-year-old woman who underwent in total 12 coronary angiographies and three percutaneous coronary intervention within 24 months because of repetitive acute coronary syndromes due to refractory spasm, dissection, restenosis all leading to end-stage heart failure, and heart transplantation. The patient died 12 days after the heart transplantation complicated by intraoperative acute thrombotic occlusion of left anterior descending artery of the graft despite normal pretransplant coronary angiography. Autopsy of the recipient heart confirmed coronary fibromuscular dysplasia with massive intimal hyperplasia and restenosis.

show abstract

Does Contrast Medium Administration in Organ Donors Affect Early Kidney Graft Function?

Cited by 17 publications

References 4 publications

Management of the Potential Organ Donor in the ICU

Management of the Potential Organ Donor in the ICU

Impact of donor coronary angiography on kidney transplantation outcomes

Intractable coronary fibromuscular dysplasia leading to end‐stage heart failure and fatal heart transplantation

Contact Info

Product

Resources

About