Does Intravenous Midazolam Dose Influence the Duration of Recovery Room Stay Following Outpatient Third Molar Surgery?

Ettinger, Kyle S.; Jacob, Adam K.; Viozzi, Christopher F.; Ess, James M. Van; Fillmore, W. Jonathan; Arce, Kevin

doi:10.1016/j.joms.2015.06.164

Cited by 3 publications

(4 citation statements)

References 17 publications

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“…( Fig. 3 ) Similarly, past studies found a significant reduction in VAS in the early postoperative hours 19 - 25 . Fig.…”

Section: Discussionsupporting

confidence: 72%

“…This study compared the efficacy of dexamethasone over adrenaline adjuvants with lignocaine 2% in IANB. Past studies used dexamethasone adjuvants in long- to intermediate-acting LAa and found significantly prolonged duration of action in brachial and femoral nerve blocks 19 - 26 . Although TMS has been most frequently used for postoperative acute pain studies 9 - 13 , there have not been many investigations conducted to determine the effectiveness of dexamethasone adjuvants with lignocaine in IANB.…”

Section: Discussionmentioning

confidence: 99%

“…Epinephrine has been used most extensively in this capacity 17 , while taking its relatively limited efficacy and cautious use into consideration. The most commonly used adjuvant drugs are dexamethasone 18 , 24 - 30 , α 2 agonists (i.e., clonidine and dexmedetomidine) 19 , 20 , opioids (i.e., buprenorphine) 29 , ketamine 24 , midazolam 25 , hyaluronidase 26 , and neostigmine 27 . Dexamethasone has been frequently used as an adjuvant for various nerve blocks, i.e., brachial plexus, femoral, intercostal, and axillary nerve blocks, during limb surgery 27 - 33 , but the exact mechanism of prolonged nerve blocks remains unclear.…”

Section: Introductionmentioning

confidence: 99%

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Effectiveness of dexamethasone or adrenaline with lignocaine 2% for prolonging inferior alveolar nerve block: a randomized controlled trial

Deo

Ahmad

Singh³

2022

JKAOMS

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Objectives: Inferior alveolar nerve block (IANB) is commonly used for mandibular dentoalveolar surgery. The objective of this study was to evaluate and compare the effectiveness of coadministration of dexamethasone (4 mg/mL) or adrenaline (0.01 mg/mL) as an adjuvant with lignocaine 2% in IANB during third molar surgery (TMS). Patients and Methods: This double-blind, randomized controlled trial was conducted between March and August 2020. The investigators screened patients needing elective TMS under local anesthesia. Based on strict inclusion and exclusion criteria, patients were enrolled in this study. These patients were assigned randomly into two study groups: dexamethasone group (DXN) or adrenaline group (ADN). Outcome variables were postoperative edema, trismus, visual analogue scale (VAS), perioperative analgesia, onset time, and duration of IANB. Results: Eighty-three patients were enrolled in this study, of whom 23 (27.7%) were eliminated or excluded during follow-up. This study thus included data from 60 samples. Mean age was 32.28±11.74 years, including 28 females (46.7%) in the ADN (16 patients, 57.1%) and DXN (12 patients, 42.9%) groups. The duration of action for DXN (mean±standard deviation [SD], 4:02:07±0:34:01 hours; standard error [SE], 0:06:00 hours; log-rank P=0.001) and for ADN (mean±SD, 1:58:34±0:24:52 hours; SE, 0:04:42 hours; log-rank P=0.001) were found. Similarly, time at which 1st analgesic consume and total number of nonsteroidal antiinflammatory drugs need to rescue postoperative analgesia was found statistically significant between study groups (t (58)=-11.95; confidence interval, -2:25:41 to -1:43:53; P=0.001). Early-hours VAS was also significantly different between the study groups. Conclusion: A single injection of dexamethasone prolongs the duration of action of lignocaine 2% IANB. Additionally, it can be used in cases where adrenaline is contraindicated.

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“…( Fig. 3 ) Similarly, past studies found a significant reduction in VAS in the early postoperative hours 19 - 25 . Fig.…”

Section: Discussionsupporting

confidence: 72%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effectiveness of dexamethasone or adrenaline with lignocaine 2% for prolonging inferior alveolar nerve block: a randomized controlled trial

Deo

Ahmad

Singh³

2022

JKAOMS

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“…Intravenous sedation is widely used effectively for oral surgery and dental procedure [1][2][3][4][5][6][7]. Dental anxiety, stress and pain can lead to hemodynamic changes such as hypertension or increased heart rate.…”

Section: Introductionmentioning

confidence: 99%

Intravenous sedation accompanied with fentanyl is effective for intramaxillary fixation in trauma patients

Ouchi¹

2016

Glob Anesth Perioper Med

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Operation of intramaxillary fixation that is required treatment of jaw fracture require long operation time, where intravenous sedation is adaptable to operation of intramaxillary fixation. Four cases were performed anesthesia and systemic management by author anesthesiologists. Anesthesia record was studied about adverse event (body movement, hemodynamic changes and pain complaint) in each case. Four patients classed in ASA physical status I. In intravenous sedation case using sedative or pentazocine combining sedative, hemodynamic changes and body movement were observed during operation. In intravenous sedation or systemic management cases of using fentanyl, body movement and hemodynamics changes were not observed during operation. Glossoptosis and hypopnea were not observed in four cases.The sedation is inhibited, if pain control is insufficient. The pain control using local anesthetic is difficult for pain of intramaxillary fixation operation. Fentanyl, specialized analgesic by high selectivity with μ receptor, is useful for operation of intramaxillary fixation, because local anesthetic is not provided enough analgesia.In conclusion, in intravenous sedation for intramaxillary fixation operation, the full agonist opioid such as the fentanyl, specialized in analgesia, is useful to provide enough analgesia.

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Anaesthesia and Perioperative Care

2020

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Does Intravenous Midazolam Dose Influence the Duration of Recovery Room Stay Following Outpatient Third Molar Surgery?

Cited by 3 publications

References 17 publications

Effectiveness of dexamethasone or adrenaline with lignocaine 2% for prolonging inferior alveolar nerve block: a randomized controlled trial

Effectiveness of dexamethasone or adrenaline with lignocaine 2% for prolonging inferior alveolar nerve block: a randomized controlled trial

Intravenous sedation accompanied with fentanyl is effective for intramaxillary fixation in trauma patients

Anaesthesia and Perioperative Care

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