Does lactoferrin, free, encapsulated or in dairy matrices, maintain its antibacterial activity after in vitro digestion?

Abad, I.; Pemán, L.; Pérez, M.D.; Grasa, L.; Sánchez, L.

doi:10.1016/j.jff.2023.105936

Cited by 2 publications

References 40 publications

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Vibration-assisted Microbead Production: A New Frontier for Biocompatible Surfaces

Yingngam,

Makewilai,

Chaisawat

et al. 2024

Medical Applications for Biocompatible Surfaces and Coatings

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The encapsulation of active pharmaceutical ingredients (APIs) in microbeads is an essential step in drug delivery; however, it is also inherently associated with the need to control particle size and drug release profiles. Nevertheless, most conventional methods of microencapsulation fail to provide consistent results. A new method called vibration-assisted microbead coating is a novel unified technique utilizing mechanical vibrations to enable the controlled, uniform coating of microbeads on APIs. This chapter discusses the technology of vibration-assisted encapsulation performed by the authors through microbead formation and the physical activity of coating APIs. This chapter focuses on achieving uniform control of the final coated surface of the API, microbead shape, size, and loading through vibration parameters. Additionally, this chapter discusses the biocompatibility and stability of the final coated surface. This new means of encapsulation has high potential for drug delivery. This method reduces most of the traditional challenges of encapsulation, if not eliminates them, and is more reliable. Based on the abovementioned findings, the authors propose the following main areas for their further work: optimisation of vibration parameters for various APIs, research into the long-term stability of the loading–release profile, and possible use of the technique in targeted drug delivery.

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Vibration-assisted Microbead Production: A New Frontier for Biocompatible Surfaces

Yingngam,

Makewilai,

Chaisawat

et al. 2024

Medical Applications for Biocompatible Surfaces and Coatings

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Is there sufficient evidence to support the health benefits of including donkey milk in the diet?

Khan,

Chen,

et al. 2024

Front. Nutr.

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Donkey milk has attracted attention due to its distinctive nutritional composition and potential health advantages, particularly because of its whey protein content, which includes lysozyme, α-lactalbumin, lactoferrin, and β-lactoglobulin and vitamin C, among other components. These elements contribute to immunoregulatory, antimicrobial, antioxidant, and anti-inflammatory properties, positioning donkey milk as a possible therapeutic option. In addition, due to the low levels of caseins, the casein-to-whey protein ratio, and the β-lactoglobulin content in donkey milk, it presents an optimal alternative for infant formula for individuals with cow’s milk allergies. Moreover, research into donkey milk’s potential for cancer prevention, diabetes management, and as a treatment for various diseases is ongoing, thanks to its bioactive peptides and components. Nevertheless, challenges such as its low production yield and the not fully understood mechanisms behind its potential therapeutic role necessitate more thorough investigation. This review consolidates the existing knowledge on the therapeutic possibilities of donkey milk, emphasizing its importance for human health and the need for more detailed studies to confirm its health benefits.

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Does lactoferrin, free, encapsulated or in dairy matrices, maintain its antibacterial activity after in vitro digestion?

Cited by 2 publications

References 40 publications

Vibration-assisted Microbead Production: A New Frontier for Biocompatible Surfaces

Vibration-assisted Microbead Production: A New Frontier for Biocompatible Surfaces

Is there sufficient evidence to support the health benefits of including donkey milk in the diet?

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