Does oral magnesium substitution relieve pregnancy-induced leg cramps?

Nygaard, Ingerid Herstad; Valbø, Annelill; Pethick, Sigrid Vingerhagen; Bøhmer, Thomas

doi:10.1016/j.ejogrb.2008.07.005

Cited by 39 publications

(26 citation statements)

References 9 publications

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“…A Cochrane database review looking at supplementing 360 mg/day (120 mg in the morning and 240 mg in the evening) of Mg in pregnancy, however, demonstrated efficacy with regard to ameliorating problems with muscle cramps [48]. On the other hand, a recent double-blind placebo controlled trial using the same dose resulted in no significant benefit [49]. Although the use of Mg is safe for muscle cramps, solid evidence is still lacking.…”

Section: Resultsmentioning

confidence: 99%

The Importance of Magnesium in Clinical Healthcare

2017

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The scientific literature provides extensive evidence of widespread magnesium deficiency and the potential need for magnesium repletion in diverse medical conditions. Magnesium is an essential element required as a cofactor for over 300 enzymatic reactions and is thus necessary for the biochemical functioning of numerous metabolic pathways. Inadequate magnesium status may impair biochemical processes dependent on sufficiency of this element. Emerging evidence confirms that nearly two-thirds of the population in the western world is not achieving the recommended daily allowance for magnesium, a deficiency problem contributing to various health conditions. This review assesses available medical and scientific literature on health issues related to magnesium. A traditional integrated review format was utilized for this study. Level I evidence supports the use of magnesium in the prevention and treatment of many common health conditions including migraine headache, metabolic syndrome, diabetes, hyperlipidemia, asthma, premenstrual syndrome, preeclampsia, and various cardiac arrhythmias. Magnesium may also be considered for prevention of renal calculi and cataract formation, as an adjunct or treatment for depression, and as a therapeutic intervention for many other health-related disorders. In clinical practice, optimizing magnesium status through diet and supplementation appears to be a safe, useful, and well-documented therapy for several medical conditions.

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Section: Resultsmentioning

confidence: 99%

The Importance of Magnesium in Clinical Healthcare

2017

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“…The sport of sailing combines static and dynamic muscular endurance, and leg cramps frequently occur, especially during prolonged competitions (see Introduction for details about the organization of the main competitions in sailing). Mg is considered valuable for the treatment of muscle cramps in general and not only in sports [47-49], and some of the sailing athletes follow such practice. Additionally, Mg (magnesium oxide) is a known medical treatment for functional constipation [50].…”

Section: Discussionmentioning

confidence: 99%

Dietary supplementation and doping-related factors in high-level sailing

Rodek

Sekulić

Kondrič

2012

Journal of the International Society of Sports Nutrition

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BackgroundAlthough dietary supplements (DSs) in sports are considered a natural need resulting from athletes’ increased physical demands, and although they are often consumed by athletes, data on DS usage in Olympic sailing are scarce. The aim of this study was to study the use of and attitudes towards DSs and doping problems in high-level competitive sailing.MethodsThe sample consisted of 44 high-level sailing athletes (5 of whom were female; total mean age 24.13 ± 6.67 years) and 34 coaches (1 of whom was female; total mean age 37.01 ± 11.70). An extensive, self-administered questionnaire of substance use was used, and the subjects were asked about sociodemographic data, sport-related factors, DS-related factors (i.e., usage of and knowledge about DSs, sources of information), and doping-related factors. The Kruskal-Wallis ANOVA was used to determine the differences in group characteristics, and Spearman’s rank order correlation and a logistic regression analysis were used to define the relationships between the studied variables.ResultsDS usage is relatively high. More than 77% of athletes consume DSs, and 38% do so on a regular basis (daily). The athletes place a high degree of trust in their coaches and/or physicians regarding DSs and doping. The most important reason for not consuming DSs is the opinion that DSs are useless and a lack of knowledge about DSs. The likelihood of doping is low, and one-third of the subjects believe that doping occurs in sailing (no significant differences between athletes and coaches). The logistic regression found crew number (i.e., single vs. double crew) to be the single significant predictor of DS usage, with a higher probability of DS consumption among single crews.ConclusionBecause of the high consumption of DSs future investigations should focus on real nutritional needs in sailing sport. Also, since athletes reported that their coaches are the primary source of information about nutrition and DSs, further studies are necessary to determine the knowledge about nutrition, DSs and doping problems among athletes and their support teams (i.e., coaches, physicians, and strength and conditioning specialists).

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“…Cramps during pregnancy are not related to pregnancy complications and are not accompanied by undesirable consequences for the fetus,[9] but the American Sleep Association considers leg cramps as one of the reasons for sleep disorders during pregnancy. [10] Sleep disorder resulting from cramps influences performance of daily activities and may lengthen the duration of pregnancy and the type of childbirth.…”

Section: Introductionmentioning

confidence: 99%

The effect of Vitamin D and calcium plus Vitamin D on leg cramps in pregnant women: A randomized controlled trial

Mansouri

Mirghafourvand

Mohammad‐Alizadeh‐Charandabi

et al. 2017

J Res Med Sci

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Background:This study intended to determine the effects of Vitamin D and calcium-Vitamin D in treating leg cramps in pregnant women.Materials and Methods:This study was conducted as a double-blind randomized controlled clinical trial on 126 participants, 18–35-year-old pregnant women with a minimum of two leg cramps per week who were referred to health-care centers in Tabriz-Iran in 2013. The participants were allocated to three 42 member groups using a randomized block design. For 42 days, the intervention groups took a 1000 unit Vitamin D pill or 300 mg calcium carbonate plus a 1000 unit Vitamin D pill, and the control group received a placebo pill every day. The participants were evaluated with regard to the frequency, length, and pain intensity of leg cramps during the week before and during the 3rd and 6th week of the intervention. The ANCOVA and repeated measurement test were used to analyze the data.Results:Results showed that controlling for the effects before the intervention, calcium-Vitamin D, and Vitamin D supplements had no effect on the frequency, length, and pain intensity of leg cramps.Conclusion:The results of this study showed that the calcium-Vitamin D and the Vitamin D supplements have no effect on the frequency, length, and pain intensity of leg cramps during the 6 weeks of the study.

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Does oral magnesium substitution relieve pregnancy-induced leg cramps?

Cited by 39 publications

References 9 publications

The Importance of Magnesium in Clinical Healthcare

The Importance of Magnesium in Clinical Healthcare

Dietary supplementation and doping-related factors in high-level sailing

The effect of Vitamin D and calcium plus Vitamin D on leg cramps in pregnant women: A randomized controlled trial

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