Does osteomalacia contribute to development of oral complications of oxalosis?

Oral Manifestations of Chronic Renal Failure Complicating a Systemic Genetic Disease: Diagnostic Dilemma. Case Report and Literature Review

“…Furthermore, the destroyed bone is replaced by uncalcified bone (osteoid), which explains the tooth mobility. 32 Some researchers have explained the high level of periodontal destruction by an existing inflamed periodontium, where vascular permeability is increased and allows a larger deposit of oxalate crystals. 11, 33 In the present case, the evident lack of oral hygiene suggested the possibility of an existent periodontal pathology that increased the deposit of crystals in periodontal tissues.…”

Salud oral en pacientes con insuficiencia renal crónica hemodializados después de la aplicación de un protocolo estomatológico

“…Otras manifestaciones características que con frecuencia refirieron estos dos pacientes son el sabor metálico y el olor amoniacal por el elevado contenido de urea en la saliva. La tendencia hemorrági-ca se evidencia en forma de petequias, equimosis y gingivorragias (8)(9)(10).…”

Oral findings associated with primary hyperoxaluria type I

“…In two of these 10 patients the diagnosis of PH could not be confirmed. The age spectrum of the 11 patients described ranges from 7 to 55 years of age (Glass, 1973;Bunte et al, 1977;Fantasia et al, 1982;Wysocki et al, 1982;Boyce et al, 1986;Lapointe and Listrom, 1988;Moskow, 1989;Hedemark et al, 1989;Rahima and DiMauro, 1992;Rinksma et al, 2008;Panis et al, 2010).…”

“…Unfortunately this mechanism cannot fully explain the phenomenon, as it does not account for oxalate deposition in non-inflamed tissues (Rinksma et al, 2008). According to Boyce et al (1986), aluminium-related osteomalacia that is observed in the course of dialysis exacerbates the periodontal damage caused by the above-mentioned mechanism. According to this publication, the oral symptoms of both the patients that were presented improved when aluminium therapy ceased and desferrioxamine treatment was initiated.…”

“…The destruction of the periodontal tissues has been attributed by Fantasia and Boyce (Fantasia et al, 1982;Boyce et al, 1986;Panis et al, 2010) to the destruction of the periodontal ligament caused by deposition of calcium oxalate crystals. According to Fantasia the increased vascular permeability of an inflamed periodontium leads to preferential deposition of calcium oxalate crystals in it.…”