Does preoperative breast MRI significantly impact on initial surgical procedure and re-operation rates in patients with screen-detected invasive lobular carcinoma?

Sinclair, Kelly; Sakellariou, Sophia; Dawson, Nuala; Litherland, Janet

doi:10.1016/j.crad.2016.03.011

Cited by 13 publications

(7 citation statements)

References 25 publications

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“…20,21 Breast MRI improves size assessment of BC in general, 22 and of ILC, pure DCIS, and DCIS components in particular (Figs 1 and 2). [22][23][24][25][26][27][28][29][30][31][32][33][34] For ILC, the reported correlation coefficients between pathologic and MRIdetermined size range from substantial to excellent (0.75-0.98). [22][23][24][25][26] For DCIS components, in a prospective study by Kuhl et al 29 on 593 consecutive women with invasive cancer, the sensitivity advantage of MRI over mammography plus ultrasound for depicting DCIS components was highly significant (P , .0001) and increased with increasing relative size and increasing nuclear grade of DCIS components.…”

Section: Imaging To Guide In-breast Surgerymentioning

confidence: 99%

Imaging in Locoregional Management of Breast Cancer

Kuhl

Lehman

Bedrosian

2020

JCO

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Section: Imaging To Guide In-breast Surgerymentioning

confidence: 99%

Imaging in Locoregional Management of Breast Cancer

Kuhl

Lehman

Bedrosian

2020

JCO

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“…The study provided evidence in support of the use of preoperative MRI in patients with ILC for surgical planning [26]. Other studies have failed to observe differences in mastectomy rates with MRI in unselected cohorts of patients, although preoperative MRI reduced reoperation rates in some studies [27]. …”

Section: Discussionmentioning

confidence: 77%

Lobular Breast Cancer and Abdominal Metastases: A Retrospective Review and Impact on Survival

et al. 2016

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Background: The predominant breast cancer subtypes, invasive lobular carcinoma (ILC) and invasive ductal carcinoma (IDC), have similar recurrence and survival rates but differing patterns of metastatic recurrence. Methods: A retrospective review of breast cancers treated at an academic medical center from 1999 to 2012 was performed. Demographic, pathologic, treatment, and follow-up data were collected for 179 ILC and 358 IDC patients (1:2 stage-matched). The median follow-up was 4.7 years. Results: The baseline characteristics were similar in the two groups. ILC was more likely to be hormone-receptor-positive/HER2-negative and mammographically occult. The number of surgical resections, breast conservation rate, systemic treatment, and taxane use was similar between the groups. The overall recurrence rate was the same. ILC recurred more often in the abdominal cavity (24.3% in ILC vs. 4.1% in IDC, p = 0.001). The disease-free survival and overall survival were equal. On multivariate analysis, age, stage of disease, hormone receptor status, and systemic therapy were associated with survival, but histology was not. Conclusions: Compared to ductal breast cancers, lobular breast cancers recur more often in the abdominal cavity. Both ILC and IDC have comparable surgical and medical treatment outcomes and survival. Our data suggest that enhanced surveillance and imaging might be useful in ILC.

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“…For this reason, a much larger tumor is often found upon surgical treatment or pathological anatomy compared to what has been predicted by previous imaging tests 16 . In order to reduce this type of unexpected findings during surgeries, more accurate imaging tests such as magnetic resonance imaging (MRI) are recommended in surgical planning for ILC patients 17 .…”

Section: Invasive Lobular Carcinomas Treated At Hospital De Clínicas mentioning

confidence: 99%

Invasive lobular carcinomas treated at Hospital de Clínicas of UFPR: incidence, characteristics and clinical outcome

Gasperin¹,

Romaniello²,

Furuie³

et al. 2018

Mastology

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Objetivo: O estudo busca caracterizar o perfil clínico epidemiológico referente às pacientes tratadas por carcinoma lobular invasor de mama (CLI) no Hospital de Clínicas da Universidade Federal do Paraná (HC-UFPR) em um período de dez anos e avaliar as variações das dimensões dos CLI nos exames de imagem quando comparadas ao real tamanho das lesões identificadas nas peças de anatomia patológica. Métodos: Foram selecionadas pacientes submetidas a procedimentos cirúrgicos de mama no HC-UFPR entre os anos de 2005 e 2014, dentre as quais 36 apresentaram diagnóstico de CLI. Seus prontuários foram analisados para avaliação de características clínicas, epidemiológicas, terapêuticas e prognósticas. Também foi avaliada a discrepância dos valores de tamanho do tumor em métodos de imagem em relação ao descrito nos laudos anatomopatológicos. Resultados: As pacientes com diagnóstico de CLI tinham média de idade no diagnóstico de 59,6 anos. O diagnóstico foi feito, em sua maioria, nos estádios clínicos II (40%) e III (26,7%). Houve maior negatividade (77,2%) para HER2 e positividade (90%) para receptor de estrógeno. O tratamento cirúrgico foi radical em 74,2% das pacientes. Em exames de imagem, 31,4% das pacientes realizaram mamografia e ultrassonografia em conjunto, 45,7% fizeram apenas um dos exames e nenhuma realizou ressonância magnética. Conclusão: Observou-se que a casuística de patologias mamárias do HC-UFPR está de acordo com a literatura em relação à incidência e às características próprias dos CLI. A análise da discrepância dos tamanhos dos tumores em exames de imagem em relação às peças cirúrgicas não obteve resultados significativos estatisticamente.

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Does preoperative breast MRI significantly impact on initial surgical procedure and re-operation rates in patients with screen-detected invasive lobular carcinoma?

Cited by 13 publications

References 25 publications

Imaging in Locoregional Management of Breast Cancer

Imaging in Locoregional Management of Breast Cancer

Lobular Breast Cancer and Abdominal Metastases: A Retrospective Review and Impact on Survival

Invasive lobular carcinomas treated at Hospital de Clínicas of UFPR: incidence, characteristics and clinical outcome

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