Does routine intravenous glucagon administration facilitate colonoscopy? A randomized trial

Comparison of Glucagon and Scopolamine Butylbromide as Premedication for Colonoscopy in Unsedated Patients

“…Conversely, other studies in which similar antispasmodic agents were administered sublingually, orally, or intravenously were unable to show any benefit. [6][7][8][9][10][11][12] The reason for these discrepancies is unclear, but it might be caused by major differences in the examiners' experience, skill, and insertion technique. Colonoscopists vary in their skill levels: they include a great number of moderately experienced hands and a handful of very experienced operators.…”

Role of intravenously administered hyoscine butyl bromide in retrograde terminal ileoscopy: A randomized, double-blinded, placebo-controlled trial

“…Glucagon has been used in lieu of hyoscine butyl bromide for achieving aperistalsis in patients undergoing ERCP [29,30] . Glucagon has also been evaluated as an adjunct in facilitating colonoscopy [31,32] . Whether glucagon can be used in lieu of hyoscine butyl bromide in achieving ileal intubation in patients undergoing colonoscopy, remains to be studied.…”

Improving the utility of colonoscopy: Recent advances in practice

“…146 Antispasmodic agents (such as hyoscine butylbromide, glucagon, and hyoscyamine) are commonly employed in gastrointestinal endoscopy, in particular, colonoscopy. Use of hyoscine butylbromide in colonoscopy has been examined as it relates to speed and ease of colonoscope insertion, 150-160 patient comfort during and post procedure, [152][153][154]156,157,[159][160][161][162][163][164] and ileal intubation. 165,166 Hyoscine butylbromide may increase mucosal view and polyp detection.…”