Does the use of DuraSeal in head and spinal surgeries reduce the risk of cerebrospinal fluid leaks and complications when compared to conventional methods of dura mater closure?

Current developments in dural repair: a focused review on new methods and materials

“…In another lumbar study involving laminotomy/discectomy with durotomy, DuraSeal-induced migration and/or swelling, not its use in an enclosed space, led to a case of postoperative cauda equina syndrome (12). A similar study by Osbun et al (13) analyzed the use of DuraSeal in head surgeries and reported that compared to suturing with or without fibrin sealant, patients undergoing head surgery using DuraSeal showed no reduction in the absolute risk of neurosurgical or incisional complications, including CSF leakage.…”

Cerebrospinal Fluid Leak as a Complication of Oculoplastic Surgery

“…As one might expect, the prevalence of iatrogenic CSF leak in neurosurgery and otolaryngology is higher. In the former, they can occur in 1-27% of cases, 8 while in the latter, surgery-related leaks constitute 20% to 30% of all encountered leaks, mainly as a complication of functional endoscopic sinus surgery (FESS). 9 The incidence, presence, and outcomes of CSF leaks complicating orbital surgery may vary greatly.…”