Does the use of trypan blue during phacoemulsification affect the intraocular pressure?

Time‐dependent morphological alterations and viability of cultured human trabecular cells after exposure to Trypan blue

“…Despite the numerous reports regarding the toxicity of TB in ocular cells of the anterior and posterior segment (corneal endothelial, lens epithelial, retinal pigment epithelium and Müller cells), there are no reports regarding the effects of TB exposure in trabecular meshwork cells in either animal or in vitro models. Ziakas et al . showed that the use of TB during phacoemulsification does not have any effect on intraocular pressure in the immediate and early postoperative periods, implying that TB has no toxic effect in trabecular meshwork cells.…”

Chromovitrectomy in Vitreous Loss During Cataract Surgery

“…Therefore, trypan blue should be removed as much as possible at the end of surgery. The use of trypan blue in cataract surgery does not increase intraocular pressure, nor cause infectious endophthalmitis, or retinal detachment [34]. Most importantly, it should be remembered that these dyes are used in potentially inflamed and/or damaged tissues.…”