Dosimetry auditing procedure with alanine dosimeters for light ion beam therapy

Ableitinger, A.; Herrmann, Rochus; Bassler, Niels; Sharpe, Peter; Ecker, Swantje; Chaudhri, Naved; Jäkel, Oliver; Georg, Dietmar

doi:10.1016/j.radonc.2013.04.029

Cited by 21 publications

(23 citation statements)

References 31 publications

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“…For end‐to‐end test procedures, two CIRS anthropomorphic phantoms were purchased and customized: a head phantom (Proton Therapy Dosimetry head phantom model 731 HN) and a pelvis phantom (Dynamic Pelvis Phantom 008P). Both phantoms were adapted to allocate different detectors (such as radiochromic films, thimble ionization chambers and Alanine detectors) in specific holders. A CT scan of the ionization chambers placed into their customized holders was performed in order to detect air pockets between the detectors and the specific holders.…”

Section: Methodsmentioning

confidence: 99%

Implementation of dosimetry equipment and phantoms at the MedAustron light ion beam therapy facility

et al. 2017

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Purpose: To describe the implementation of dosimetry equipment and phantoms into clinical practice of light ion beam therapy facilities. This work covers not only standard dosimetry equipment such as computerized water scanners, films, 2D-array, thimble, and plane parallel ionization chambers, but also dosimetry equipment specifically devoted to the pencil beam scanning delivery technique such as water columns, scintillating screens or multilayer ionization chambers. Method: Advanced acceptance testing procedures developed at MedAustron and complementary to the standard acceptance procedures proposed by the manufacturer are presented. Detailed commissioning plans have been implemented for each piece of dosimetry equipment and include an estimate of the overall uncertainty budget for the range of clinical use of each device. Some standard dosimetry equipment used in many facilities was evaluated in detail: for instance, the recombination of a 2D-array or the potential use of a microdiamond detector to measure reference transverse dose profiles in water in the core of the primary pencil beams and in the low-dose nuclear halo (over four orders of magnitude in dose). Results: The implementation of dosimetry equipment as described in this work allowed determining absolute spot sizes and spot positions with an uncertainty better than 0.3 mm. Absolute ranges are determined with an uncertainty comprised of 0.2-0.6 mm, depending on the measured range and were reproduced with a maximum difference of 0.3 mm over a period of 12 months using three different devices. Conclusion: The detailed evaluation procedures of dosimetry equipment and phantoms proposed in this work could serve as a guidance for other medical physicists in ion beam therapy facilities and also in conventional radiation therapy.

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Section: Methodsmentioning

confidence: 99%

Implementation of dosimetry equipment and phantoms at the MedAustron light ion beam therapy facility

et al. 2017

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“…There is also an expansion of techniques such as stereotactic radiotherapy, electronic brachytherapy and proton therapy. 78 A significant number of centres will be offering these services, and there will be a requirement to identify and support the standards that can be achieved. Future audits and clinical trials will need to address the new technologies which are on the horizon and develop suitable approaches and measurement techniques.…”

Section: Looking Aheadmentioning

confidence: 99%

Radiotherapy dosimetry audit: three decades of improving standards and accuracy in UK clinical practice and trials

Clark

Aird

Bolton

et al. 2015

BJR

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Dosimetry audit plays an important role in the development and safety of radiotherapy. National and large scale audits are able to set, maintain and improve standards, as well as having the potential to identify issues which may cause harm to patients. They can support implementation of complex techniques and can facilitate awareness and understanding of any issues which may exist by benchmarking centres with similar equipment. This review examines the development of dosimetry audit in the UK over the past 30 years, including the involvement of the UK in international audits. A summary of audit results is given, with an overview of methodologies employed and lessons learnt. Recent and forthcoming more complex audits are considered, with a focus on future needs including the arrival of proton therapy in the UK and other advanced techniques such as four-dimensional radiotherapy delivery and verification, stereotactic radiotherapy and MR linear accelerators. The work of the main quality assurance and auditing bodies is discussed, including how they are working together to streamline audit and to ensure that all radiotherapy centres are involved. Undertaking regular external audit motivates centres to modernize and develop techniques and provides assurance, not only that radiotherapy is planned and delivered accurately but also that the patient dose delivered is as prescribed.

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“…8 Since this time the detector has been mainly used in photon dosimetry, 9 but also in charged particle beams. [10][11][12][13] Most studies on neutrons have been carried out with fast neutron energies in the MeV region and without distinction of dose components. [14][15][16] Charged and uncharged ionizing particles generate radicals in alanine.…”

Section: Proton Dose D Pmentioning

confidence: 99%

The alanine detector in BNCT dosimetry: Dose response in thermal and epithermal neutron fields

et al. 2015

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The alanine detector can be used without difficulty in neutron fields. The response has been understood with the model used which includes the relative effectiveness. Results and the corresponding discussion lead to the conclusion that application in neutron fields for medical purpose is limited by its sensitivity but that it is a useful tool as supplement to other detectors and verification of neutron source descriptions.

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Dosimetry auditing procedure with alanine dosimeters for light ion beam therapy

Cited by 21 publications

References 31 publications

Implementation of dosimetry equipment and phantoms at the MedAustron light ion beam therapy facility

Implementation of dosimetry equipment and phantoms at the MedAustron light ion beam therapy facility

Radiotherapy dosimetry audit: three decades of improving standards and accuracy in UK clinical practice and trials

The alanine detector in BNCT dosimetry: Dose response in thermal and epithermal neutron fields

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