Double Autologous Stem Cell Transplantation in a Case of Non-secretory Multiple Myeloma

Abstract

Multiple myeloma represents a challenge for hematologists because it has become more frequent at a young age in recent years. This is why autologous stem cell transplantation is included in the standard treatment of myeloma patients. We present the case of a 39-year-old patient who was diagnosed with non-secretory myeloma with double autologous transplantation and underwent neurosurgery for spinal cord compression caused by a plasmocytoma at D5 level. We present the evolution and complexity of this very difficult case.

New Treatment Methods in Multiple Myeloma

“…2,7 A second transplantation is recommended if the patient did not reach complete remission or very good partial remission (VGPR), or relapses in less than 12 months after the first transplantation. 19 The conditioning regimens can be performed with melphalan 140 mg/m 2 combined with total body irradiation or melphalan 200 mg/m 2 . 5 In the Clinic of Hematology and Transplant of Tîrgu Mureș, the conditioning treatment is performed only with melphalan, without irradiation.…”