Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain

Elzaki, Wail M.; Abubakr, Neamat Hassan; Ziada, Hassan; Ibrahim, Y. E.

doi:10.1016/j.joen.2016.02.014

Cited by 37 publications

(43 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…. Our group also reported a significant pain reduction using the combination of Ibuprofen/Paracetamol in a double‐blinded placebo controlled randomized clinical trial (RCT) .…”

Section: Introductionmentioning

confidence: 82%

“…We recently reported on the efficiency of non‐opioid analgesics, following initial endodontic therapy, in a double‐blind placebo‐controlled clinical trial . The same sample is analysed here for the secondary outcomes, specifically, gender and arch influences on pain reduction.…”

Section: Methodsmentioning

confidence: 99%

“…Both postgraduate studies boards of the Faculty of Dentistry and the Ethical Research Committee of medical health sciences, University of Khartoum, Sudan, granted the ethical clearance. The CONSORT guidelines and flow chart have been followed and reported with the primary outcomes in our previous study .…”

Section: Methodsmentioning

confidence: 99%

“…A number of pain intensity measurements exist, extensive research has been carried out regarding the most ideal. We previously reported on post‐endodontic pain using the numerical rating scale (NRS) and the verbal rating scale (VRS) . The NRS is an 11‐, 21‐ or 101‐point scale with end points identifying the extremes of ‘no pain’ and ‘as bad as it could be’ or ‘the worst pain’.…”

Section: Introductionmentioning

confidence: 99%

“…The NRS is an 11‐, 21‐ or 101‐point scale with end points identifying the extremes of ‘no pain’ and ‘as bad as it could be’ or ‘the worst pain’. We also used the verbal rating scale (VRS‐4); which is made up of a list of descriptors, which represent the level of pain intensity . Being a subjective scale, its association with disease could be indirect.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Gender and arch effects on the use of non‐opioid analgesics for post endodontic pain reduction

et al. 2017

Self Cite

View full text Add to dashboard Cite

This study aimed to evaluate the secondary outcomes of gender and arch and their impact on pain reduction following initial endodontic therapy. 185 medications, including placebo were prepared, and 170 participants completed the trial. Group 1, received a single dose of Paracetamol alone (G-1), Group 2 received combined Ibuprofen/Paracetamol (G-2). Group 3 received combined Mefenamic acid/Paracetamol (G-3), group 4 received combined Diclofenac K/Paracetamol (G-4) and Group 5 received a placebo (G-5). There were no statistically significant differences in pain reduction between males and females whilst there were statistically significant differences between them and the placebo group. All combinations of Paracetamol performed better in pain reduction than the placebo among females, while there were no statistically significant differences among males. In conclusion, there were no differences in pain reduction between males and females, and arch for the tested analgesics taken immediately following initial endodontic therapy in teeth with irreversible pulpitis.

show abstract

“…. Our group also reported a significant pain reduction using the combination of Ibuprofen/Paracetamol in a double‐blinded placebo controlled randomized clinical trial (RCT) .…”

Section: Introductionmentioning

confidence: 82%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations