Double-network composites based on inorganic fillers reinforced dextran-based hydrogel with high strength

In situ forming double-crosslinked hydrogels with highly dispersed short fibers for the treatment of irregular wounds

“…The characteristic peaks could be seen at 9.60–9.65 ppm and 8.45–8.50 ppm, which corresponded to the aldehyde group. 48 And the peaks at 4.10–5.70 ppm were attributed to the hemiacetal group, indicating successful oxidation of dextran. 49 The degree of oxidation of ODex was 62.4%, which was measured by the hydroxylamine hydrochloride titration method.…”

Regulating the release of Mg-MOF from degradable bone cement by coating Mg-MOF with oxidized dextran/gelatin

“…As the water bonded by OD/Gel, which would in turn prolonged the hydration time of the cement. 31 In addition, Fig. 3(b) shows the mechanical strength of the composite bone cements.…”

“…37 In addition, OD/Gel was not cytotoxic, and the dissolved OD and Gel could provide a good growth environment for cells. 31 It had been confirmed that gelatin contained the Arg–Gly–Asp (RGD) sequence, which could promote cell adhesion and proliferation, and the promotion effect was more significant with the increase of gelatin content. 38 The above could also prove that the OD/Gel@Mg-MOF composite bone cement had good cell compatibility and could promote cell proliferation.…”

“…29 After oxidation, dextran could react with gelatin by Schiff base reaction to form a hydrogel, which had good biodegradability and could effectively slow down the drug release. 30,31 For example, Yan et al 32 used dextran with different molecular weights to cross-link gelatin to prepare OD/Gel composite hydrogels. High molecular weight OD cross-linked hydrogels could release curcumin in a more controllable manner, and the structural characteristics of the corresponding hydrogels could be adjusted by the molecular weight of the cross-linking agent to achieve effective and controllable drug release.…”

Shungite/poly(vinyl alcohol) hybrid hydrogels: An efficient adsorption material for rare earth metals in aqueous media

“…In recent years, inorganic fillers were integrated within the 3D structure of organic-based hydrogel which is yielded to hybrid hydrogels with enhanced mechanical durability and adsorption properties due to increasing specific surface area and surface functional groups. 14 For instance, Guo et al prepared carbon dots embedded alginate (ALG-CDs) hydrogel beads. They found the adsorption capacity of ALG-CDs as 201.21 mg/g for Gd 3+ ion and Gd 3+ ion showed a strong affinity rather than Al 3+ , Co 2+ , Ni 2+ , Zn 2+ , and Mg 2+ .…”