2023
DOI: 10.21203/rs.3.rs-3443958/v1
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Down-regulated FDX1 inhibited the proliferation and migration of renal cell carcinoma cells

Zhijie Bai,
Chun Wang,
Mingpeng Zhang
et al.

Abstract: Background With the intensive study of cell death, a copper-related cell death mechanism has been uncovered that is different from other forms of cell death, which researchers have named cuproptosis. Ferredoxin1 (FDX1) is a key gene in cuproptosis. Available studies have shown that FDX1 expression is down-regulated in a variety of solid tumors and plays an inhibitory role in tumors. However, studies related to the role of FDX1 in renal cell carcinoma (RCC) and its mechanism are scarce and still need to be fur… Show more

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