2017
DOI: 10.1016/j.chroma.2017.06.019
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Doxycycline as a new chiral selector in capillary electrophoresis

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Cited by 26 publications
(13 citation statements)
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“…Three classes of low molecular weight compounds were reported as CS. These are CS with a central ion (i.e., ligand exchangers [78,79], an ion-pair selector [80]), ILs [31,81,82] and a tetracycline antibiotic [83]. An IL implemented in a ligand exchanger is discussed under ILs.…”
Section: Low Molecular Weight Compoundsmentioning
confidence: 99%
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“…Three classes of low molecular weight compounds were reported as CS. These are CS with a central ion (i.e., ligand exchangers [78,79], an ion-pair selector [80]), ILs [31,81,82] and a tetracycline antibiotic [83]. An IL implemented in a ligand exchanger is discussed under ILs.…”
Section: Low Molecular Weight Compoundsmentioning
confidence: 99%
“…Doxycycline is a common antibiotic that is already available in generic drug formulations. Recently, it was nicely explored as a new CS in EKC [83]. This was perhaps motivated by the several stereogenic centers and functional groups in its structure.…”
Section: Low Molecular Weight Compoundsmentioning
confidence: 99%
“…In addition to that, the running cost of LC-MS/MS methods is inherently high and it cannot be moved to application sites which adds a burden of sample transfer to central laboratories [14,15]. Other laboratory based methods include electrophoresis [16][17][18][19][20] and enzyme assay (ELISA) [21,22].…”
Section: Introductionmentioning
confidence: 99%
“…The most used methods for the detection of antibiotics are chromatographic [ 6 , 7 , 8 , 9 ], due to the automation, accurate quantification, simultaneous detection, and the high specificity based on the structural information of the analytes. Other methods for antibiotic determination include electrophoresis [ 10 , 11 , 12 , 13 , 14 ], diode array [ 15 , 16 ] or enzyme immunosorbent assay (ELISA) [ 17 , 18 , 19 ]. Meanwhile, for the detection of bacteria, the culture-based method remains the golden standard, although a good number of methods based on nucleic acid (e.g., based on polymerase chain reaction (PCR)) or immunologic reactions have been developed.…”
Section: Introductionmentioning
confidence: 99%