Draft Genome Sequence of a Lactobacillus gasseri Strain Isolated from the Catheterized Urine of a Healthy Postmenopausal Woman

Abstract

Urinary microbiome composition has been found to associate with health status and to change with age. Lactobacillus gasseri is one of the most frequently found lactic acid bacteria in the vaginal and urinary tracts of women. Here, we report a draft genome sequence of a urinary L. gasseri strain isolated from a healthy postmenopausal woman.

Synthesis of current pediatric urinary microbiome research

“…To date, no functional studies analyzing behavior or interactions of isolated species from pediatric urobiome were reported in either in vitro or in vivo models, though there have been a few functional studies of the common bacteria found in the adult urobiomes (76)(77)(78)(79)(80)(81). However, the genomes of numerous urobiome commensal strains have been established and analyzed bioinformatically, even with establishing new speciation of bacteria specific to the human bladder (8,(82)(83)(84)(85)(86)(87).…”

Draft genomes of Lactobacillus delbrueckii and Klebsiella pneumoniae coexisting within a female urinary bladder

“…Urinary bacterial pathogens have been characterized for decades, while the normal urinary microbiome has only been explored for the last decade with culture-independent sequencing methods and advanced culturing techniques ( 1 , 2 ). With patient consent and approval of the Duke University Medical Center Institutional Review Board (#Pro00083917), we used Enhanced Quantitative Urine Culture technique to isolate commensal bacteria from the urinary bladder of asymptomatic, post-menopausal female patients with or without diagnosis of recurrent urinary tract infections (rUTI) via aseptic urinary catheterization ( 1 , 3 – 5 ).…”