Draft Genome Sequence of an Endophytic Actinoplanes Species, Encoding Uncommon trans -Acyltransferase Polyketide Synthases

Abstract

Actinoplanes is an endophytic actinobacterium isolated from the medicinal plant Amphipterygium adstringens. The strain draft genome sequence reveals a gene cluster involved in the biosynthesis of a hybrid trans-acyltransferase (AT) polyketide, an unconventional bioactive metabolite never reported before in the genus Actinoplanes.

Diversity and Applications of Endophytic Actinobacteria of Plants in Special and Other Ecological Niches

“…Frequencies for the presence of biosynthetic genes in the endophytic actinobacteria of the plant Dracaena cochinchinensis Lour was 29.4, 70.6, and 23.5%, for PKS-I, PKS-II, and NRPS respectively (Salam et al, 2017 ). Gene cluster encoding hybrid trans-acyltransferase (AT) polyketide was identified during the genome analysis of endophytic actinobacterium, Actinoplanes isolated from the plant Amphipterygium adstringens for the first time (Centeno-Leija et al, 2016 ). In genome analysis of the endophyte, Streptomyces kebangsaanensis , it was established that 24 gene clusters were involved in the production of a novel phenanzine.…”

Hidden Microbial Helpers Living Inside Plants: Getting to Know Endophytes and Some of Their Applications in Our Daily Lives

“…From other medicinal plant species, like "Granadilla" (Callicarpa acuminata) and the "Copal" tree (Bursera simaruba), scientists found endophytes that produce chemicals that can kill weeds and fight against fungi that cause plant diseases [4]. Endophytes were also found from the medicinal tree "Cuachalalate" (Amphiterygium adstringens), and these endophytes could be used in the production of chemicals to treat cancer or bacterial infections in humans [5]. From the medicinal plant "Mano de oso" (Dendropanax arboreous), scientists discovered endophytes that could produce chemicals to fight against noxious microbes that make humans sick [6].…”