Draft Genome Sequence of Streptomyces scabrisporus NF3, an Endophyte Isolated from
            <i>Amphipterygium adstringens</i>

Vázquez‐Hernández, Melissa; Ceapă, Corina Diana; Rodríguez-Luna, Stefany Daniela; Rodríguez‐Sanoja, Romina; Sánchez, Sergio

doi:10.1128/genomea.00267-17

Cited by 9 publications

(6 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…GMKU 363 harbor three type I PKS gene clusters associated with the synthesis of linfuranone (Komaki et al, 2015 ). Streptomyces scabrisporus NF3, an endophyte isolated from Amphipterygium adstringens , carries at least 50 gene clusters for the synthasis of polyketides and nonribosomal peptides (Vazquez-Hernandez et al, 2017 ). Genome sequence of Streptomyces sp.…”

Section: Biosynthetic Gene Clusters In Endophytic Actinobacteriamentioning

confidence: 99%

“…Similarly, Streptomyces sp. XY006, an endophyte isolated from Tea ( Camellia sinensis ) had 27 possible secondary metabolite biosynthetic gene clusters encoding for antimycin, melanin, informatipeptin, albaflavenone, and roseoflavin (Vazquez-Hernandez et al, 2017 ). Genome mining of Streptomyces wadayamensis A23, an endophytic strain showed the presence of biosynthetic gene clusteres for antimycins and candicidin (Angolini et al, 2016 ).…”

Section: Biosynthetic Gene Clusters In Endophytic Actinobacteriamentioning

confidence: 99%

“…Streptomyces sp. XY006 genome sequence revealed the presence of genes associated with synthesis of indole-3-acetic acid, 1-aminocyclopropane-1-carboxylate deaminase, mineral phosphate solubilization, transport and assimilation, and also genes involved in fungal cell-wall degradation, such as a family 19 chitinases (Vazquez-Hernandez et al, 2017 ). Genome sequence of Streptomyces sp.…”

Section: Biosynthetic Gene Clusters In Endophytic Actinobacteriamentioning

confidence: 99%

See 2 more Smart Citations

Diversity and Applications of Endophytic Actinobacteria of Plants in Special and Other Ecological Niches

2018

View full text Add to dashboard Cite

Actinobacteria are wide spread in nature and represent the largest taxonomic group within the domain Bacteria. They are abundant in soil and have been extensively explored for their therapeutic applications. This versatile group of bacteria has adapted to diverse ecological habitats, which has drawn considerable attention of the scientific community in recent times as it has opened up new possibilities for novel metabolites that may help in solving some of the most challenging problems of the day, for example, novel drugs for drug-resistant human pathogens, affordable means to maintain ecological balance in various habitats, and alternative practices for sustainable agriculture. Traditionally, free dwelling soil actinobacteria have been the subject of intensive research. Of late, symbiotic actinobacteria residing as endophytes within the plant tissues have generated immense interest as potential source of novel compounds, which may find applications in medicine, agriculture, and environment. In the light of these possibilities, this review focuses on the diversity of endophytic actinobacteria isolated from the plants of extreme habitats and specific ecological niches. Furthermore, an attempt has been made to assign chemical class to the compounds obtained from endophytic actinobacteria. Potential therapeutic applications of these compounds and the utility of endophytic actinobacteria in agriculture and environment are discussed.

show abstract

Section: Biosynthetic Gene Clusters In Endophytic Actinobacteriamentioning

confidence: 99%

Section: Biosynthetic Gene Clusters In Endophytic Actinobacteriamentioning

confidence: 99%

Section: Biosynthetic Gene Clusters In Endophytic Actinobacteriamentioning

confidence: 99%

See 1 more Smart Citation

Diversity and Applications of Endophytic Actinobacteria of Plants in Special and Other Ecological Niches

2018

View full text Add to dashboard Cite

show abstract

“…Their analysis suggested variations between KM-4927 T and DSM 41855 strains with changes in some of their polyketide biosynthetic genes [32]. Furthermore, a recent comparison made by our research group between the strains DSM 41855 and NF3, suggested important differences in their putative gene clusters encoding for secondary metabolites production [33]. Finally, the presence of 2 clades in the S. scabrisporus phylogenetic tree, with more than 60% bootstrap value, may support significant dissimilarities within this species.…”

Section: Discussionmentioning

confidence: 89%

Streptomyces scabrisporus, an endophyte isolated from Amphipterygium adstringens as producer of an anthracycline active against different cancer cell lines

et al. 2018

Self Cite

View full text Add to dashboard Cite

show abstract

“…The genome sequence of SS NF3 was previously reported [ 28 ]. The genome is linear and has a 71.61% of GC content ( Fig 1 ), falling into the normal range for a streptomycete and a size of 10.95 Mbp, falling in the top 5% of known Streptomyces genomes ( S1 Fig ).…”

Section: Resultsmentioning

confidence: 99%

Genome mining of Streptomyces scabrisporus NF3 reveals symbiotic features including genes related to plant interactions

et al. 2018

Self Cite

View full text Add to dashboard Cite

Endophytic bacteria are wide-spread and associated with plant physiological benefits, yet their genomes and secondary metabolites remain largely unidentified. In this study, we explored the genome of the endophyte Streptomyces scabrisporus NF3 for discovery of potential novel molecules as well as genes and metabolites involved in host interactions. The complete genomes of seven Streptomyces and three other more distantly related bacteria were used to define the functional landscape of this unique microbe. The S. scabrisporus NF3 genome is larger than the average Streptomyces genome and not structured for an obligate endosymbiotic lifestyle; this and the fact that can grow in R2YE media implies that it could include a soil-living stage. The genome displays an enrichment of genes associated with amino acid production, protein secretion, secondary metabolite and antioxidants production and xenobiotic degradation, indicating that S. scabrisporus NF3 could contribute to the metabolic enrichment of soil microbial communities and of its hosts. Importantly, besides its metabolic advantages, the genome showed evidence for differential functional specificity and diversification of plant interaction molecules, including genes for the production of plant hormones, stress resistance molecules, chitinases, antibiotics and siderophores. Given the diversity of S. scabrisporus mechanisms for host upkeep, we propose that these strategies were necessary for its adaptation to plant hosts and to face changes in environmental conditions.

show abstract

Draft Genome Sequence of Streptomyces scabrisporus NF3, an Endophyte Isolated from Amphipterygium adstringens

Cited by 9 publications

References 16 publications

Diversity and Applications of Endophytic Actinobacteria of Plants in Special and Other Ecological Niches

Diversity and Applications of Endophytic Actinobacteria of Plants in Special and Other Ecological Niches

Streptomyces scabrisporus, an endophyte isolated from Amphipterygium adstringens as producer of an anthracycline active against different cancer cell lines

Genome mining of Streptomyces scabrisporus NF3 reveals symbiotic features including genes related to plant interactions

Contact Info

Product

Resources

About