Draft Genome Sequences of 12 Feline Bartonella henselae Isolates

Woudstra, Cédric; Fach, Patrick; Chomel, Bruno B; Haddad, Nadia; Boulouis, Henri Jean

doi:10.1128/genomea.00075-17

Cited by 4 publications

(4 citation statements)

References 5 publications

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“…Bartonella henselae exhibits heterogeneity with two serotypes (Houston-1 and Marseille) [7, 8] which overlap genotypes I (Houston I) and genotype II (Marseille), identified according to 16S rRNA gene sequences [8–11]. In addition, within the above genotypes, two genogroups (Houston I and Marseille II) with more genotypes were delineated based on the heme-binding protein ( Pap31 ) encoding gene [10].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of a 10% imidacloprid/4.5% flumethrin polymer matrix collar in reducing the risk of Bartonella spp. infection in privately owned cats

et al. 2019

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BackgroundBartonella henselae, Bartonella clarridgeiae and the rare Bartonella koehlerae are zoonotic pathogens, with cats being regarded as the main reservoir hosts. The spread of the infection among cats occurs mainly via fleas and specific preventive measures need to be implemented. The effectiveness of a 10% imidacloprid/4.5% flumethrin polymer matrix collar (Seresto®, Bayer Animal Health), registered to prevent flea and tick infestations, in reducing the risk of Bartonella spp. infection in privately owned cats, was assessed in a prospective longitudinal study.MethodsIn March-May 2015 [Day 0 (D0)], 204 privately-owned cats from the Aeolian Islands (Sicily) were collared (G1, n = 104) or left as controls (G2, n = 100). The bacteraemia of Bartonella spp. was assessed at enrolment (D0) and study closure (D360) by PCR and DNA sequencing both prior to and after an enrichment step, using Bartonella alpha proteobacteria growth medium (BAPGM).ResultsA total of 152 cats completed the study with 3 in G1 and 10 in G2 being positive for Bartonella spp. Bartonella henselae genotype I ZF1 (1.35%) and genotype II Fizz/Cal-1 (6.76%) as well as B. clarridgeiae (5.41%) were detected in cats of G2. Bartonella clarridgeiae was the only species detected in G1. Based on the yearly crude incidence of Bartonella spp. infection (i.e. 3.85% in G1 and 13.51% in G2; P = 0.03) the Seresto® collar achieved a preventative efficacy of 71.54%. The incidence of Bartonella spp. infection was more frequent in flea-infested cats (6/33, 18.18%) than in uninfested ones (7/112, 5.88%) (P = 0.036).ConclusionsCats living in the Aeolian Islands are exposed to B. henselae and B. clarridgeiae. The Seresto® collar provided significant risk reduction against Bartonella spp. infection in outdoor cats under field conditions. Such a preventative tool could be a key contribution for decreasing the risk of Bartonella spp. infection in cats and thus ultimately to humans.

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Section: Introductionmentioning

confidence: 99%

Effectiveness of a 10% imidacloprid/4.5% flumethrin polymer matrix collar in reducing the risk of Bartonella spp. infection in privately owned cats

et al. 2019

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“…In France, the Marseille genotype has been shown to be dominant in central France, while the Houston genotype is dominant in the south of France [ 32 ]. There is evidence that these two genotypes vary in their zoonotic potential: Houston has been associated with more severe clinical manifestations than those induced by Marseille [ 60 ].…”

Section: Discussionmentioning

confidence: 99%

Bartonella Infections in Cats and Cat Fleas in Lithuania

et al. 2021

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Bartonella are vector-borne parasitic bacteria that cause zoonotic infections in humans. One of the most common infections is cat-scratch disease caused by Bartonella henselae and Bartonella clarridgeiae. Cats are the major reservoir for these two species of bacteria, while cat fleas are vectors for the transmission of infection agents among cats. The aim of the present study was to investigate the presence of Bartonella infections in stray and pet cats and in cat fleas in Lithuania. Blood samples were taken from 163 cats presented in pet clinics and animal shelters. A total of 102 fleas representing two species, Ctenocephalides felis and Ctenocephalides canis, were collected from 12 owned cats that live both outdoors and indoors. Bartonella DNA in samples was detected using a nested PCR targeting the 16S–23S rRNA intergenic spacer (ITS) region. Bartonella DNA was detected in 4.9% (8/163) of the cats and 29.4% (30/102) of the fleas. Sequence analysis of the ITS region showed that the cats and fleas were infected with B. henselae, B. clarridgeiae and Bartonella sp., closely related to B. schoenbuchensis. This study is the first report on the prevalence and molecular characterization of Bartonella spp. in cats and cat fleas in Lithuania.

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“…We need to monitor the disease, be aware of its geographic diversity, and better understand its pathobiology. 53,54 The ophthalmic community must be proactive, starting with clinical recognition. Residency programs can familiarize residents with the disease's clinical aspects and the laboratory test needed to make the diagnosis.…”

Section: Discussionmentioning

confidence: 99%

The Continuing Ophthalmic Challenge of Bartonella henselae

Albert¹,

Salman

Winthrop³

et al. 2021

Ophthalmology Science

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Purpose: To better understand the history and epidemiology of Bartonella henselae infections of the eye and adnexa, and their relationship to cat scratch disease (CSD). We also assess B. henselae infection as a public health threat.Methods: We reviewed the available literature concerning B. henselae infections of the eye and CSD, and attempted calculation of the incidence and prevalence of both B. henselae eye infections and CSD from the database of the Rochester Epidemiology Project.Results: It took nearly a century of determined effort to reveal that Henri Parinaud's oculoglandular syndrome (POGS) (1889) and Leber's stellate retinitis (1916) were the result of B. henselae infection and are subtypes of CSD. These ocular infections remain of clinical, epidemiologic, and public health concern to ophthalmologists with many unanswered questions. Their incidence and prevalence have yet to be accurately determined. Our attempt to achieve this through the Rochester Epidemiology Project database suggests a major obstacle is inconsistent with nonunanimous diagnostic terminology and coding.Conclusions: Modern serologic testing and molecular diagnostic techniques offer ophthalmologists the opportunity to make B. henselae infection of the eyes an area of "precision medicine." For this to happen, greater awareness and teaching about this disease, updated terminology, and a greater clinical and research effort are required.

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Draft Genome Sequences of 12 Feline Bartonella henselae Isolates

Cited by 4 publications

References 5 publications

Effectiveness of a 10% imidacloprid/4.5% flumethrin polymer matrix collar in reducing the risk of Bartonella spp. infection in privately owned cats

Effectiveness of a 10% imidacloprid/4.5% flumethrin polymer matrix collar in reducing the risk of Bartonella spp. infection in privately owned cats

Bartonella Infections in Cats and Cat Fleas in Lithuania

The Continuing Ophthalmic Challenge of Bartonella henselae

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