Draft of the clinical practice guidelines “Adrenal incidentaloma”

Beltsevich, D. G.; Трошина, Е. А.; Мельниченко, Г. А.; Platonova, Nadezhda; Ladygina, Daria; Chevais, Anastassia

doi:10.14341/serg12712

Cited by 6 publications

(2 citation statements)

References 124 publications

(190 reference statements)

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“…Согласно методическим рекомендациям, среди новообразований надпочечников выделяют: 1) адренокортикальные образования: рак или аденома; 2) опухоли мозгового вещества надпочечников: феохромоцитома; 3) метастатическое поражение надпочечников; 4) другие образования: кисты, липомы, тератомы и прочие; 5) «псевдонадпочечниковые» образования: опухоли почек, поджелудочной железы, селезенки, желудка, правой доли печени, забрюшинных лимфатических узлов или кровеносных сосудов [ 4 ].…”

Section: Discussionunclassified

“…В большинстве случаев биопсия надпочечника малоинформативна, а при АКР строго противопоказана. При проведении биопсии происходит разрыв капсулы узла, что в случае злокачественного новообразования приводит к диссеминации процесса и ухудшению прогноза заболевания, поэтому пункционная биопсия может быть применима только при неоперабельной опухоли в случае, если результат патоморфологического исследования может повлиять на тактику лечения пациентов [ 4 ][ 6 ]. Тем не менее в метаанализе 32 исследований I. Bancos и соавт.…”

Section: Discussionunclassified

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Metastatic lesions of the adrenal glands. The experience of Endocrinology Research Center.

Pachuashvili,

Roslyakova,

Porubayeva

et al. 2023

Probl Endokrinol (Mosk)

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Differentiation between benign, primary and secondary malignant tumors is a critical problem in the clinical treatment of adrenal tumors, especially in patients with isolated adrenal lesions. In most cases, the correct diagnosis can be established microscopically with standard staining with hematoxylin and eosin. However, there are cases when it is almost impossible to distinguish metastasis from primary adrenal cancer, so an accurate diagnosis requires an immunohistochemical examination.This article presents five unique observations of secondary adrenal tumors that were diagnosed by us in the current surgical material: metastasis of clear cell renal cell carcinoma, follicular variant of papillary thyroid cancer, metastasis of keratinizing squamous cell carcinoma of the cervix, lymphoepithelioma-like carcinoma of the bladder, as well as malignant mesothelioma. Taking into account the extreme rarity of the presented observations, we present an analysis of the literature data.

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Section: Discussionunclassified

Metastatic lesions of the adrenal glands. The experience of Endocrinology Research Center.

Pachuashvili,

Roslyakova,

Porubayeva

et al. 2023

Probl Endokrinol (Mosk)

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Primary hyperaldosteronism: the choice in favor of conservative surgery

Annayev,

Stegniy,

Geltser

et al. 2023

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Primary hyperaldosteronism (PHA) is the most common cause of secondary arterial hypertension among endocrine disorders. Given that patients with this pathology are at a higher risk of developing fatal and non-fatal cardiovascular events, early diagnosis and timely treatment are of great importance. Currently, the two main forms of PHA are aldosterone-producing adenoma and bilateral adrenal hyperplasia, which are treated with laparoscopic adrenalectomy or pharmacotherapy with mineralocorticoid receptor antagonists. Although most patients experience restoration of their functional and metabolic status after surgical intervention, some may develop postoperative adrenal insuffi ciency, which requires long-term hormone replacement therapy. This review examines the options for organ-preserving surgeries, such as partial adrenalectomy and selective embolization of the adrenal artery.

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Problems of diagnosis and treatment of Connshing syndrome

Annaev,

Geltser,

Stegniy

et al. 2024

jour

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Despite the fact that it has been almost 50 years since the first description of aldosterone-cortisol-producing adrenal adenomas (Connshing syndrome), there are still many unresolved issues regarding the diagnosis and treatment of this condition. The presented clinical case confirms the complexity of recognizing this disease due to the frequent absence of its manifesting clinical symptoms and the lack of information acquired from standard laboratory tests. In these cases, the method of comparative selective venous blood sampling from the adrenal glands plays a significant role in the differential diagnosis of rare forms of primary hyperaldosteronism. Analysis of clinical cases presented in the scientific literature from 2000 to 2023 showed that partial adrenalectomy is the method of choice for surgical treatment of this pathology, which is associated with minimal risk of postoperative complications.

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Draft of the clinical practice guidelines “Adrenal incidentaloma”

Cited by 6 publications

References 124 publications

Metastatic lesions of the adrenal glands. The experience of Endocrinology Research Center.

Metastatic lesions of the adrenal glands. The experience of Endocrinology Research Center.

Primary hyperaldosteronism: the choice in favor of conservative surgery

Problems of diagnosis and treatment of Connshing syndrome

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