Drainage versus defense

Abstract

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Lead acetate deteriorates the improvement effect of L-arginine and tetrahydrobiopterin on endothelin-1 receptors activity in rat aorta

“…the hydroxylases, ether lipid oxidase, and the three nitric oxide synthase (NOS) isoenzymes. Also, BH4 acts as an antioxidant and neutralizes RNS and ROS 16 . According to our knowledge, no published evidence is yet available to explain how BH4 and LA combination affects ET-1 receptors activity in the intact and lead-treated aortic rings.…”