This study explores the transformative impact of social media and AI on healthcare communication, emphasizing their transformative potential in information dissemination, patient engagement, and misinformation management. It highlights how social media platforms provide real-time updates and patient support, while AI technologies like machine learning and natural language processing revolutionize data analysis and personalized care. Despite these benefits, integrating these tools raises ethical concerns, such as privacy issues, data security risks, and informed consent complexities. It addresses challenges like data interoperability, infrastructure sufficiency, and system scalability, emphasizing the need for comprehensive provider training and unbiased AI algorithms. It also examines AI's role in curbing misinformation while balancing ethical considerations and free speech. The study advocates for a collaborative approach to ensure innovative and ethically sound healthcare communication, improve patient outcomes, and foster a more equitable and efficient healthcare system.