Drinking patterns and hydration biomarkers among young adults with different levels of habitual total drinking fluids intake in Baoding, Hebei Province, China: a cross-sectional study

Zhang, Jianfen; Zhang, Na; Wang, Yan; Liang, Shuxin; Liu, Shufang; Du, Songming; Xu, Yifan; He, Haibo; Cai, Hao; Ma, Guansheng

doi:10.1186/s12889-020-08558-z

Cited by 11 publications

(26 citation statements)

References 52 publications

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“…Blood pressure (BP) was measured twice to the nearest 2 mmHg, with at least a 15 min rest period before measurement by a professional nurse using an electronic sphygmomanometer (HEM-7051, Omron, Jiangsu, China). Two measurements were taken after 2 min intervals [ 24 ]. (BMI: weight (kg)/height squared (m)).…”

Section: Methodsmentioning

confidence: 99%

Effects of Water Restriction and Supplementation on Cognitive Performances and Mood among Young Adults in Baoding, China: A Randomized Controlled Trial (RCT)

Zhang

et al. 2021

Nutrients

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The brain is approximately 75% water. Therefore, insufficient water intake may affect the cognitive performance of humans. The present study aimed to investigate the effects of water restriction and supplementation on cognitive performances and mood, and the optimum amount of water to alleviate the detrimental effects of dehydration, among young adults. A randomized controlled trial was conducted with 76 young, healthy adults aged 18–23 years old from Baoding, China. After fasting overnight for 12 h, at 8:00 a.m. of day 2, the osmolality of the first morning urine and blood, cognitive performance, and mood were measured as a baseline test. After water restriction for 24 h, at 8:00 a.m. of day 3, the same indexes were measured as a dehydration test. Participants were randomly assigned into four groups: water supplementation group (WS group) 1, 2, or 3 (given 1000, 500, or 200 mL purified water), and the no water supplementation group (NW group). Furthermore, participants were instructed to drink all the water within 10 min. Ninety minutes later, the same measurements were performed as a rehydration test. Compared with the baseline test, participants were all in dehydration and their scores on the portrait memory test, vigor, and self-esteem decreased (34 vs. 27, p < 0.001; 11.8 vs. 9.2, p < 0.001; 7.8 vs. 6.4, p < 0.001). Fatigue and TMD (total mood disturbance) increased (3.6 vs. 4.8, p = 0.004; 95.7 vs. 101.8, p < 0.001) in the dehydration test. Significant interactions between time and volume were found in hydration status, fatigue, vigor, TMD, symbol search test, and operation span test (F = 6.302, p = 0.001; F = 3.118, p = 0.029; F = 2.849, p = 0.043; F = 2.859, p = 0.043; F = 3.463, p = 0.021) when comparing the rehydration and dehydration test. Furthermore, the hydration status was better in WS group 1 compared to WS group 2; the fatigue and TMD scores decreased, and the symbol search test and operation span test scores increased, only in WS group 1 and WS group 2 (p < 0.05). There was no significant difference between them (p > 0.05). Dehydration impaired episodic memory and mood. Water supplementation improved processing speed, working memory, and mood, and 1000 mL was the optimum volume.

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Section: Methodsmentioning

confidence: 99%

Effects of Water Restriction and Supplementation on Cognitive Performances and Mood among Young Adults in Baoding, China: A Randomized Controlled Trial (RCT)

Zhang

et al. 2021

Nutrients

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“…A cross-sectional study conducted among young adults revealed that participants with higher total drinking fluids had better hydration status, with lower urine osmolality and higher urine volume than those with lower total drinking fluids. However, no differences were found in plasma biomarkers [17]. Similarly, young females with fluid intake of <1.2 L/d produced a smaller amount of more concentrated urine than participants with 2-4 L/d fluids intake [18].…”

Section: Introductionmentioning

confidence: 74%

“…The urine osmolality was used to determine the hydration status for people in free-living conditions, as well as the urine color [13][14][15][16]. It was showed that the urinary biomarkers varied according to the fluids' intake, both in China and other countries [17,18]. Studies also demonstrated that the hydration biomarkers, including the urinary and the plasma biomarkers, were significant in terms of predicting health outcomes.…”

Section: Introductionmentioning

confidence: 99%

The Relationships between Water Intake and Hydration Biomarkers and the Applications for Assessing Adequate Total Water Intake among Young Adults in Hebei, China

Zhang

et al. 2021

Nutrients

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Water is an essential nutrient for humans. A cross-sectional study was conducted among 159 young adults aged 18–23 years in Hebei, China. The total drinking fluids and water from food were obtained by 7-day 24 h fluid intake questionnaires and the duplicate portion method, respectively. Pearson’s correlation coefficients were performed to determine the relationship between fluid intake and 24 h urinary biomarkers and plasma biomarkers. A multivariable partial least squares (PLS) model was used to identify the key predictors in modeling the total water intake (TWI) with 24 h urine biomarkers. Logistic regressions of the TWI against binary variables were performed, and the receiver operating characteristic curve (ROC) was analyzed to determine the cutoff value of the TWI for the optimal hydration status and dehydration without adjustments to favor either the sensitivity or specificity. In total, 156 participants (80 males and 76 females) completed the study. Strong relationships were found between the total drinking fluids, TWI, and 24 h urine biomarkers among young adults, especially for the 24 h urine volume (r = 0.784, p < 0.001; r = 0.747, p < 0.001) and osmolality (r = −0.589, p < 0.001; r = −0.477, p < 0.001), respectively. As for the FMU and plasma biomarkers, no strong relationships were found. The percentages of the variance in TWI explained by the PLS model with 13 urinary biomarkers were 66.9%. The optimal TWI values for assessing the optimal hydration and dehydration were 2892 mL and 2482 mL for young males, respectively, and 2139 mL and 1507 mL for young females, respectively. Strong relationships were found between the TWI, total drinking fluids, and 24 h urine biomarkers, but not with the FMU and plasma biomarkers, among young adults, including males and females. The 24 h urine biomarkers were more sensitive than the first morning urinary biomarkers in reflecting the fluid intake. The TWI was a reliable index for assessing the hydration statuses for young adults in free-living conditions.

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“…Water is one of the main components of the human body, which is vital for the performance of physiological processes, thermoregulation, and transport of nutrients [1,6,7,8]. Water consumption is influenced by numerous factors, including temperature, humidity, as well as the level of physical activity and lifestyle [15,18,21,27]. The most vulnerable groups to dehydration are children and adolescents, who are prone to excessive water loss, especially during physical activity and may not be aware of the need to restore lost fluid [26,28].…”

Section: Discussionmentioning

confidence: 99%

“…The endocrine system is involved in a number of water metabolism processes, optimizing the flow and excretion of fluid in the body. The pancreas, as an organ of the digestive and endocrine systems, undergoes pronounced structural changes under conditions of dehydration [4,5,7], as well as during the use of alcohol, opioids and smoking [15,18,20,21,27]. Therefore, an important issue today is the understanding of risk factors, physiological and pathogenetic links of pancreas diseases, systematization and expansion of data in the world literature on this issue [6,16,20,25].…”

Section: Introductionmentioning

confidence: 99%

Quantitative changes in the microstructure of the pancreas under the influence of sublethal dehydration, subsequent readaptation and correction

Kovchun

2021

Rep. of Morph.

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Dehydration is a pathological condition caused by insufficient water intake and is accompanied by metabolic disorders that have significant consequences for human health and performance. The endocrine system takes part in a number of functions of the water exchange system, optimizing body fluid volume. In the literature, there is no systematic data on changes in the pancreas under conditions of various types of dehydration. This article is devoted to the study of structural changes in the pancreas in conditions of sublethal degrees of various types of dehydration, followed by readaptation and correction with a drug that has anti-ischemic, membrane-stabilizing, antioxidant, hepatoprotective and immunomodulatory properties that allow to normalize protein, carbohydrate and lipid metabolism. The purpose of the study was to research the features of changes in the endocrine and exocrine parenchyma of the pancreas by the method of morphometry of histological preparations under conditions of sublethal dehydration with subsequent readaptation and correction with thiazotic acid morpholinium salt. The study group consisted of 60 mature male rats, which were simulated sublethal degree of general, cellular and extracellular dehydration by the method of A.D.Soboleva, V.Z.Sikora, J.Ya.Bodnar. After reaching a severe degree of dehydration, part of the rats were transferred to a regular drinking diet, the second part received a corrector drug for 14 days. The animals were withdrawn from the experiment by decapitation under anesthesia on 24th, 44th and 104th days in accordance with the type of dehydration. After analyzing the results obtained, it was found that there were no significant differences in most morphometric parameters under conditions of exposure to sublethal dehydration in comparison with subsequent readaptation. Significant changes in the area of the islets of Langerhans and the area of nuclei of exocrinocytes were revealed under conditions of exposure to various types of sublethal dehydration in comparison with readaptation and correction; in all experimental groups. Other morphometric parameters of the pancreatic parenchyma had changes of varying statistical significance, which depended on the type of dehydration. It has been established that the use of the thiazotic acid morpholinium salt leads to partial restoration of the structural components of the pancreatic parenchyma in comparison with the period of readaptation.

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Drinking patterns and hydration biomarkers among young adults with different levels of habitual total drinking fluids intake in Baoding, Hebei Province, China: a cross-sectional study

Cited by 11 publications

References 52 publications

Effects of Water Restriction and Supplementation on Cognitive Performances and Mood among Young Adults in Baoding, China: A Randomized Controlled Trial (RCT)

Effects of Water Restriction and Supplementation on Cognitive Performances and Mood among Young Adults in Baoding, China: A Randomized Controlled Trial (RCT)

The Relationships between Water Intake and Hydration Biomarkers and the Applications for Assessing Adequate Total Water Intake among Young Adults in Hebei, China

Quantitative changes in the microstructure of the pancreas under the influence of sublethal dehydration, subsequent readaptation and correction

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