2019
DOI: 10.3390/bios9020080
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Droplets for Sampling and Transport of Chemical Signals in Biosensing: A Review

Abstract: The chemical, temporal, and spatial resolution of chemical signals that are sampled and transported with continuous flow is limited because of Taylor dispersion. Droplets have been used to solve this problem by digitizing chemical signals into discrete segments that can be transported for a long distance or a long time without loss of chemical, temporal or spatial precision. In this review, we describe Taylor dispersion, sampling theory, and Laplace pressure, and give examples of sampling probes that have used… Show more

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Cited by 20 publications
(12 citation statements)
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“… Common microfluidic flow types: ( a ) co-flow [ 96 ], ( b ) cross-flow [ 96 ], ( c ) flow-focusing [ 96 ], ( d ) continuous flow [ 97 ], ( e ) slug flow [ 98 ], and ( f ) annular flow [ 98 ]. Reprinted from open-access sources.…”
Section: Figurementioning
confidence: 99%
“… Common microfluidic flow types: ( a ) co-flow [ 96 ], ( b ) cross-flow [ 96 ], ( c ) flow-focusing [ 96 ], ( d ) continuous flow [ 97 ], ( e ) slug flow [ 98 ], and ( f ) annular flow [ 98 ]. Reprinted from open-access sources.…”
Section: Figurementioning
confidence: 99%
“…2,5-Dihydroxybenzoic acid (DHB), which is a MALDI matrix, is applied to the dried droplets as shown in Fig. 6 (Feng et al 2019 ; Kussmann and Roepstorff 2000 ; Küster et al 2013 ; Wang et al 2015 ). This technique is mainly used for bioanalysis reactions such as enzymatic reaction, proteins and peptide analysis.…”
Section: Types Of Microfluidic Chips Based On Device Configurationmentioning
confidence: 99%
“…Áèîñåíñîð ïðåäñòàâëÿåò ñîáîé àíàëèòè÷åñêèé èíñòðóìåíò, â êîòîðîì â êà÷åñòâå "÷óâñòâèòåëüíîãî ýëåìåíòà" èñïîëüçóåòñÿ áèîëîãè÷åñêèé ìàòåðèàë (ôåðìåíòû, àíòèòåëà, îðãàíåëëû, íóêëåèíîâûå êèñëîòû, êëåòêè èëè òêàíè) [1,2]. Ñ ïîìîùüþ áèîñåíñîðîâ îïðåäåëÿþò ñîäåðaeàíèå ðàç-ëè÷íûõ ìîëåêóë â ñðåäàõ [3][4][5][6][7][8][9]. Îäíèì èç ïðèìåíåíèé áèîñåíñîðîâ ÿâëÿåòñÿ äåòåêöèÿ ãîìîñåðèíëàêòîíîâ äëÿ èçó÷åíèÿ ðåàêöèé ÷óâñòâà êâîðóìà ó Pseudomonas aeruginosa.…”
Section: ôãáîó âî íîâîñèáèðñêèé ãîñóäàðñòâåííûé àãðàðíûé óíèâåðñèòåòunclassified