Drug-Induced Acne

Kazandjieva, Jana; Tsankov, Nikolaï

doi:10.1007/978-3-540-69375-8_33

Cited by 3 publications

(3 citation statements)

References 24 publications

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“…The following patients were excluded from the study: those with signs of hyperandrogenism such as polycystic ovaries, androgenic alopecia, or hirsutism 8 ; smokers 9 ; subjects with diseases that affect IGF‐1 levels such as diabetes, 10 metabolic syndrome, 11 Laron syndrome, and acromegaly 12 ; underweight and overweight subjects, pregnancy, 12 conditions that affect liver 13 or thyroid 16 function, high levels of stress; celiac disease and inflammatory bowel diseases 17 ; patients on hormonal therapy, or taking corticosteroid, 18 lithium, 19 growth hormone, 20 metformin, 21 vitamin B12, 22 whey proteins, 23 and estrogenic‐progestogens 24 …”

Section: Methodsmentioning

confidence: 99%

Do acne treatments affect insulin‐like growth factor‐1 serum levels? A clinical and laboratory study on patients with acne vulgaris

Rodighiero

Bertolani

Saleri

et al. 2020

Dermatologic Therapy

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Acne is a chronic inflammatory disease affecting sebaceous gland follicles. Lately, acne has considered an insulin‐like growth factor‐1 (IGF‐1) mediated disease. Recent research demonstrated that IGF‐1 levels decrease after 3 months of isotretinoin. The purpose of our study is evaluating the influence of acne treatments on IGF‐1 serum levels. Forty‐six subjects with acne vulgaris aged 14 to 30 years were subdivided into three groups according to their severity of acne and treated following the European Dermatology Forum guidelines. IGF‐1 was measured in patients before and after the treatment and then compared to the IGF‐1 of a healthy population of the same age. IGF‐1 resulted higher in patients than in controls but there was not a statistically significant variation after treatment. To the best of our knowledge, this is the first study evaluating the influence of topical and systemic acne treatment on IGF‐1 serum levels. In contrast with the literature, our results suggest that common therapies for acne are not able to significantly modify IGF‐1 serum levels.

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Section: Methodsmentioning

confidence: 99%

Do acne treatments affect insulin‐like growth factor‐1 serum levels? A clinical and laboratory study on patients with acne vulgaris

Rodighiero

Bertolani

Saleri

et al. 2020

Dermatologic Therapy

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“…Acne is an inflammatory and multifactorial skin disease . Different external and internal factors, including air pollution, aggressive skincare products, medication, mechanical, hormonal and familial factors and, more recently, lifestyle and stress, have been suggested as having an impact on acne …”

Section: Introductionmentioning

confidence: 99%

Acne and nutrition: hypotheses, myths and facts

Claudel¹,

Auffret²,

Leccia

et al. 2018

Acad Dermatol Venereol

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Acne is an inflammatory and multifactorial skin disease. Different external and internal factors, including air pollution, aggressive skincare products, medication, mechanical, hormonal and familial factors and, more recently, lifestyle and stress, have been suggested as having an impact on acne. Moreover, for many years nutrition was believed to cause or worsen acne. Over the last decades, however, it has become a dermatological doctrine that there is no direct association between diet and acne. Even if recent research has allowed to identify certain nutritional elements and behaviour that may impact on acne, including the excessive intake of dairy products and hyperglycaemic food, modern lifestyle nutrition, obesity and eating disorders, knowledge about the role of nutrition in the physiopathology of acne still remains sparse and hypotheses and myths continue to dominate the debate. Thus, further clinical and translational research is necessary to investigate and confirm the association between nutrition and acne.

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“…However, despite beneficial action, the therapy may carry side-effects, affecting both life conditions and compliance of patients in a considerable way. Lithium's side-effects include hypercalcaemia, gastrointestinal, dermatological, cardiovascular, renal, as well as thyroid and parathyroid disorders [2,7,8,9,10,11,12]. Research has revealed its harmful influence on the functions of key organs, including liver and kidney [2,10,13,14] with the latter being particularly vulnerable [3,15,16].…”

Section: Introductionmentioning

confidence: 99%