Drug-Induced Hyperglycemia

Luna, Beatriz

doi:10.1001/jama.286.16.1945

Cited by 157 publications

(72 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Otherwise, drugs associated with weight gain such as various antipsychotics (chlorpromazine, haloperidole, clozapine, olanzapine, risperidone, quetiapine) have the potential to worsen glucose tolerance and thereby seemingly decrease antidiabetic drug efficacy [Amin and Suksomboon, 2014]. The same applies to hormonal contraceptives, protease inhibitors, niacin and calcineurin inhibitors, which are other drugs with considerable potential to contribute to a deterioration of blood glucose control [Luna and Feinglos, 2001]. Glycemic control may be altered with use of sympathomimetic agents, leading to decreased effects of antidiabetic agents.…”

Section: Drugs Affecting the Efficacy Of Antidiabetic Agents In Generalmentioning

confidence: 99%

Clinically and pharmacologically relevant interactions of antidiabetic drugs

May

Schindler

2016

Therapeutic Advances in Endocrinology

110

View full text Add to dashboard Cite

Abstract:Patients with type 2 diabetes mellitus often require multifactorial pharmacological treatment due to different comorbidities. An increasing number of concomitantly taken medications elevate the risk of the patient experiencing adverse drug effects or drug interactions. Drug interactions can be divided into pharmacokinetic and pharmacodynamic interactions affecting cytochrome (CYP) enzymes, absorption properties, transporter activities and receptor affinities. Furthermore, nutrition, herbal supplements, patient's age and gender are of clinical importance. Relevant drug interactions are predominantly related to sulfonylureas, thiazolidinediones and glinides. Although metformin has a very low interaction potential, caution is advised when drugs that impair renal function are used concomitantly. With the exception of saxagliptin, dipeptidyl peptidase-4 (DPP-4) inhibitors also show a low interaction potential, but all drugs affecting the drug transporter P-glycoprotein should be used with caution. Incretin mimetics and sodium-glucose cotransporter-2 (SGLT-2) inhibitors comprise a very low interaction potential and are therefore recommended as an ideal combination partner from the clinical-pharmacologic point of view.

show abstract

Section: Drugs Affecting the Efficacy Of Antidiabetic Agents In Generalmentioning

confidence: 99%

Clinically and pharmacologically relevant interactions of antidiabetic drugs

May

Schindler

2016

Therapeutic Advances in Endocrinology

110

View full text Add to dashboard Cite

show abstract

“…99 Stress hyperglycemia is observed with the use of beta blocking agents, due to reduction in insulin secretion from pancreatic β cells. 99 Chronic administration of pentamidine can result in SH, due to impaired insulin release and pancreatic β-cell destruction. 98 Calcineurin inhibitors, such as tacrolimus and cyclosporine, can result in SH and post-transplant diabetes, due to decreases in insulin biosynthesis and release.…”

Section: Medications and Stress Hyperglycemiamentioning

confidence: 99%

Stress Hyperglycemia in Pediatric Critical Illness: The Intensive Care Unit Adds to the Stress!

Srinivasan

2012

J Diabetes Sci Technol

View full text Add to dashboard Cite

Abbreviations: (BG), blood glucose, (CBP) cardiopulmonary bypass, (EN) enteral nutrition, (ECLS) extracorporeal life support, (FFA) free fatty acids, (GIR) glucose infusion rate, (GLUT) glucose transporter protein, (GH) growth hormone, (IGF-1) insulin-like growth factor-1, (ICU) intensive care unit, (IL-1) interleukin-1, (IL-6) interleukin-6, (PN) parenteral nutrition, (ROS) reactive oxygen species, (RRT) renal replacement therapy, (SH) stress hyperglycemia, (TGC) tight glucose control, (TNF-α) tumor necrosis factor-α

show abstract

“…New treatment strategies need to be developed to overcome these health-related issues. [58] Hence, selection of novel microorganism and its preparations for using as probiotics has become a critical demand in health care which has attracted attention of many researchers to identify and study their biological effect.…”

Section: Discussionmentioning

confidence: 99%

Untitled

Prabhakar¹

2017

IJGP

View full text Add to dashboard Cite

Diabetes mellitus is commonly known worldwide by the name of diabetes which occurs in all age groups. About >90% of diagnosed patient specially are Type-2 diabetes. The hallmark of Type 2 diabetes developments is increased insulin resistance, whereas Type 1 is related to less production of insulin which leads to uncontrolled hyperglycemia. Hyperglycemia slowly produces mild-to-very serious complications in patient mainly affecting vital organs such as blood vessels, eyes, neurons, nephrons, heart, and brain which increase the risk of heart attack, retinopathy, nephropathy, neuropathy, and stroke. Proper management of hyperglycemia is a key to prevent from diabetes and its complications. This concept has attracted many researchers to target various cells and tissue through special remedy so that hyperglycemia can be managed and complications can be reduced. The patient shows numerous side effects during therapy. There is craving demand for the proper cure of diabetes by sufferers. In this aspect, probiotics can be more helpful if proper research and formulation are done. Probiotics are good microorganism which can control hyperglycemia and its complications by utilizing and modifying glucose before absorption. Appropriate research is required to make strategy for searching and formulating good microorganism to be used as probiotics for the regulation of blood glucose and prevention from complexity.

show abstract

Drug-Induced Hyperglycemia

Cited by 157 publications

References 42 publications

Clinically and pharmacologically relevant interactions of antidiabetic drugs

Clinically and pharmacologically relevant interactions of antidiabetic drugs

Stress Hyperglycemia in Pediatric Critical Illness: The Intensive Care Unit Adds to the Stress!

Untitled

Contact Info

Product

Resources

About