Drug loading into β-cyclodextrin granules using a supercritical fluid process for improved drug dissolution

Preparation of inclusion complex of piroxicam with cyclodextrin by using supercritical carbon dioxide

“…Drug References geraniol, mustard oil [12] acetaminophen [13] piroxicam [14,15] miconazole [15,16,17,18,19,20] Eflucimibe [21,22] ibuprofen [23,24,25,26,27,28,29] naproxen [28,30,31,32] flurbiprofen [28] citral, thymol, carvacrol [33] imazalil [34] salicylic acid [35] azobenzene [36] budesonide [37,38,39] indomethacin [40] polyaniline [41] cholesterol [42] arylphosphines [43] itraconazole [44,45,46] 2 sodium salts [47] hydroxyflavone [48] benzocaine [50, 49,] bupivacaine, and mepivacaine [50] simvastatin [51] several triphenyl phosphine derivatives [52] all-trans-lycopene [53] 15 carbohydrates [54] human serum immunoglobulin G …”

Novel pH-sensitive microgels prepared using salt bridge

“…They can form inclusion complex with many kinds of molecules. ␤-Cyclodextrin (␤-CD) with seven glucose monomers in a ring was reported to be suitable for the widest range of drugs (Salmaso et al, 2007;Mura et al, 2002;Hussein et al, 2008). Besides, the hydrogel based on ␤-CD was also reported to show a high drug loading efficiency and local sustained drug release ability (Rodriguez-Tenreiro et al, 2006).…”

Release profile of ibuprofen in β-cyclodextrin complexes from two different solid dosage forms

“…The presence of IB as an inclusion complex is responsible for the difference between the reference formulation (IBLAC) and the commercial formulations (Com1 and Com2). The characteristics of the particles resulting from the method of preparation and the quick disintegration of the IBβCD K70 tablet made the difference from the other formulation (IBβCD FD) [8,30,31]. For the other times considered (60 and 180 min) results have shown a more pronounced increase in the IB released from IBβCD FD tablets.…”